Immunoglobulin (Ig) A deficiency is characterized by undetectable levels of serum IgA and
normal levels of other immunoglobulins (IgG, IgM) in patients more than 4 years of age …

Patients with immunoglobulin (Ig) A deficiency develop autoantibodies against IgA, which
render them vulnerable to severe anaphylactic reactions when transfused with conventional …

A 45-year-old woman diagnosed with immunoglobu-lin A (IgA) deficiency during blood
donation and undiagnosed with anti-IgA antibodies possession underwent emergency total …

Purpose When exposed in the perioperative period to blood components containing
immunoglobulin (Ig) A IgA-sensitized IgA-deficient patients are at an increased risk of …

Selective deficiency of serum IgA is the most common immunodeficiency in humans; when
immunodeficient individuals receive blood transfusions a severe anaphylactoid reaction can …

IgA deficiency is a relatively common congenital immunodeficiency in children. It can either
be asymptomatic or lead to frequent infections, most often of the sinuses and lungs …

Severe anaphylactic or allergic reactions may occur during blood transfusion to patients who
are IgA-deficient and have anti-IgA in their blood, particularly those with class-specific …

The incidence of selective IgA deficiency in general population is 1: 400 to 1: 750. When IgA
immunodeficient person receives transfusion of blood or plasma, a severe allergic reaction …

Anaphylactoid transfusion reaction following the administration of incompatible blood
products can be life threatening, but accounts for only a very small proportion of all …

Anaphylactic transfusion reactions are acute, potentially life-threatening events with
generalized signs and symptoms. Usually IgE mediated they may also result from antigen …