High energy diets can have a detrimental effect on brain plasticity. For example, a high
fructose diet impairs spatial memory in male rats. The aim of the present study was to …

Over the past three decades there has been a substantial increase in the amount of fructose
consumed by North Americans. Recent evidence from rodents indicates that hippocampal …

Objectives: The purpose of the current study is to directly compare a diet high in fat with a
diet high in fructose. This side-by-side comparison will allow us to determine the …

Excessive consumption of sugar sweetened drinks is proposed to produce functional
changes in the hippocampus, leading to perturbations in learning and memory. In this study …

Caffeine is a psychostimulant frequently consumed by adults and children, often in
combination with high levels of sugar. Chronic pretreatment with either substance can …

The effects of intake of a palatable food source on oral amphetamine intake were assessed
in adult male Long-Evans rats. In Experiment 1, six rats were given an amphetamine sulfate …

Previous research has shown that diets high in fat and sugar [aka, Western diets (WD)] can
impair performance of rats on hippocampal-dependent learning and memory problems, an …

Patients with type-2 diabetes, obesity, and metabolic syndrome have a significantly
increased risk of developing depression. Dysregulated metabolism may contribute to the …

Adolescence is a critical developmental period, concerning anatomical, neurochemical and
behavioral changes. Moreover, adolescents are more sensitive to the long-term deleterious …

The consequences of excessive fructose intake extend beyond those of metabolic disorder
to changes in emotional regulation and cognitive function. Long-term consumption of …