Evolving concepts of the pathogenesis of rheumatoid arthritis with focus on the early and late stages

F Coutant, P Miossec - Current opinion in rheumatology, 2020 - journals.lww.com
Evolving concepts of the pathogenesis of rheumatoid arthriti... : Current Opinion in
Rheumatology Evolving concepts of the pathogenesis of rheumatoid arthritis with focus on …

[引用][C] Invasive fibroblast‐like synoviocytes in rheumatoid arthritis. Passive responders or transformed aggressors?

GS Firestein - Arthritis & Rheumatism, 1996 - Wiley Online Library
Among the panoply of cells in the rheumatoid synovium, increasing attention has been
directed toward non-T cell elements as potential therapeutic targets. While the precise role …

Molecular and cellular heterogeneity in rheumatoid arthritis: mechanisms and clinical implications

J Zhao, S Guo, SJ Schrodi, D He - Frontiers in immunology, 2021 - frontiersin.org
Rheumatoid arthritis is an autoimmune disease that exhibits significant clinical
heterogeneity. There are various treatments for rheumatoid arthritis, including disease …

Novel insights into macrophage diversity in rheumatoid arthritis synovium

MA Boutet, G Courties, A Nerviani, B Le Goff… - Autoimmunity …, 2021 - Elsevier
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease affecting joints and
causing progressive damage and disability. Macrophages are of critical importance in the …

Cell-cell interactions in rheumatoid arthritis synovium

DA Fox, A Gizinski, R Morgan… - Rheumatic Disease …, 2010 - rheumatic.theclinics.com
Although the cause of rheumatoid arthritis (RA) remains unknown, insights into the
pathogenesis of RA have been achieved by careful study of inflammatory, immune, and …

Distinct stromal and immune cell interactions shape the pathogenesis of rheumatoid and psoriatic arthritis

A Floudas, CM Smith, O Tynan, N Neto… - Annals of the …, 2022 - ard.bmj.com
Objectives Immune and stromal cell communication is central in the pathogenesis of
rheumatoid arthritis (RA) and psoriatic arthritis (PsA), however, the nature of these …

Cells of the synovium in rheumatoid arthritis. Macrophages

RW Kinne, B Stuhlmüller, GR Burmester - Arthritis research & therapy, 2007 - Springer
The multitude and abundance of macrophage-derived mediators in rheumatoid arthritis and
their paracrine/autocrine effects identify macrophages as local and systemic amplifiers of …

Recent advances in understanding the pathogenesis of rheumatoid arthritis: new treatment strategies

AL Mueller, Z Payandeh, N Mohammadkhani… - Cells, 2021 - mdpi.com
Rheumatoid arthritis (RA) is considered a chronic systemic, multi-factorial, inflammatory, and
progressive autoimmune disease affecting many people worldwide. While patients show …

Activation of synoviocytes

U Müller-Ladner, RE Gay, S Gay - Current opinion in …, 2000 - journals.lww.com
The evaluation of molecular pathways has revealed various novel insights into rheumatoid
arthritis pathophysiology during the past year. In addition, there is an increasing tendency …

[PDF][PDF] One year in review 2017: pathogenesis of rheumatoid arthritis

F Angelotti, A Parma, G Cafaro, R Capecchi… - Clin Exp …, 2017 - clinexprheumatol.org
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease influenced by both
genetic and environmental factors. It has been postulated that a high-risk genetic …