Epstein–Barr virus as a leading cause of multiple sclerosis: mechanisms and implications

K Bjornevik, C Münz, JI Cohen, A Ascherio - Nature Reviews Neurology, 2023 - nature.com
Epidemiological studies have provided compelling evidence that multiple sclerosis (MS) is a
rare complication of infection with the Epstein–Barr virus (EBV), a herpesvirus that infects …

Epstein–Barr virus and multiple sclerosis

M Salvetti, G Giovannoni, F Aloisi - Current opinion in neurology, 2009 - journals.lww.com
Epstein–Barr virus and multiple sclerosis : Current Opinion in Neurology Epstein–Barr virus
and multiple sclerosis : Current Opinion in Neurology Log in or Register Subscribe to journalSubscribe …

The role of Epstein-Barr virus in the etiology of multiple sclerosis: a current review

K Ruprecht - Expert review of clinical immunology, 2020 - Taylor & Francis
Introduction: Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the
central nervous system. While its exact etiology is unknown, it is generally believed that MS …

Epstein–Barr virus and multiple sclerosis: association or causation?

J Pakpoor, G Giovannoni… - Expert review of …, 2013 - Taylor & Francis
Multiple sclerosis (MS) is a multifactorial disease in which both genetic and environmental
factors and their interactions underlie causation. The current evidence base supports a …

Epstein–Barr virus and multiple sclerosis. From evidence to therapeutic strategies

S Fernández-Menéndez, M Fernández-Morán… - Journal of the …, 2016 - Elsevier
Multiple sclerosis is caused by a complex interaction between genetic predisposition and
environmental factors. Epstein–Barr virus (EBV) is an environmental risk factor that is …

Trigger, pathogen, or bystander: the complex nexus linking Epstein–Barr virus and multiple sclerosis

GP Owens, JL Bennett - Multiple Sclerosis Journal, 2012 - journals.sagepub.com
A causal role for virus infection in the pathophysiology of multiple sclerosis (MS) has been
suggested and widely debated since the landmark epidemiologic studies of Kurtzke …

Epstein-Barr virus is present in the brain of most cases of multiple sclerosis and may engage more than just B cells

A Hassani, JR Corboy, S Al-Salam, G Khan - PloS one, 2018 - journals.plos.org
Multiple sclerosis (MS) is a chronic neuroinflammatory condition of the central nervous
system (CNS). It is a major cause of neurological disability in young adults, particularly …

Epstein–Barr virus infection and multiple sclerosis: a review

A Ascherio, KL Munger - Journal of Neuroimmune Pharmacology, 2010 - Springer
Epstein–Barr virus (EBV) infection results in a life-long persistence of the virus in the host's B-
lymphocytes and has been associated with numerous cancers including Burkitt's lymphoma …

Epstein–Barr virus and multiple sclerosis

SS Soldan, PM Lieberman - Nature Reviews Microbiology, 2023 - nature.com
Epstein–Barr virus (EBV) is a ubiquitous human lymphotropic herpesvirus with a well-
established causal role in several cancers. Recent studies have provided compelling …

Primary infection with the Epstein‐Barr virus and risk of multiple sclerosis

LI Levin, KL Munger, EJ O'reilly, KI Falk… - Annals of …, 2010 - Wiley Online Library
To determine whether multiple sclerosis (MS) risk increases following primary infection with
the Epstein‐Barr virus (EBV), we conducted a nested case‐control study including 305 …