The nature and dynamics of spermatogonial stem cells
DG De Rooij - Development, 2017 - journals.biologists.com
Spermatogonial stem cells (SSCs) are crucial for maintaining spermatogenesis throughout
life, and understanding how these cells function has important implications for …
life, and understanding how these cells function has important implications for …
A revised Asingle model to explain stem cell dynamics in the mouse male germline
Spermatogonial stem cells (SSCs) and progenitor spermatogonia encompass the
undifferentiated spermatogonial pool in mammalian testes. In rodents, this population is …
undifferentiated spermatogonial pool in mammalian testes. In rodents, this population is …
Molecular regulation of spermatogonial stem cell renewal and differentiation
JA Mäkelä, RM Hobbs - Reproduction, 2019 - rep.bioscientifica.com
The intricate molecular and cellular interactions between spermatogonial stem cells (SSCs)
and their cognate niche form the basis for life-long sperm production. To maintain long-term …
and their cognate niche form the basis for life-long sperm production. To maintain long-term …
A single-cell view of spermatogonial stem cells
K Tan, MF Wilkinson - Current opinion in cell biology, 2020 - Elsevier
Spermatogonial stem cells (SSCs) are essential for long-term spermatogenesis and are the
subject of considerable clinical interest, as 'SSC therapy'has the potential to cure some …
subject of considerable clinical interest, as 'SSC therapy'has the potential to cure some …
Spermatogonial stem cell regulation and spermatogenesis
This article will provide an updated review of spermatogonial stem cells and their role in
maintaining the spermatogenic lineage. Experimental tools used to study spermatogonial …
maintaining the spermatogenic lineage. Experimental tools used to study spermatogonial …
Open niche regulation of mouse spermatogenic stem cells
S Yoshida - Development, growth & differentiation, 2018 - Wiley Online Library
In mammalian testes, robust stem cell functions ensure the continual production of sperm. In
testicular seminiferous tubules, spermatogenic stem cells (SSC s) are highly motile and are …
testicular seminiferous tubules, spermatogenic stem cells (SSC s) are highly motile and are …
Mechanisms regulating mammalian spermatogenesis and fertility recovery following germ cell depletion
Mammalian spermatogenesis is a highly complex multi-step process sustained by a
population of mitotic germ cells with self-renewal potential known as spermatogonial stem …
population of mitotic germ cells with self-renewal potential known as spermatogonial stem …
Spermatogonial stem cells: updates from specification to clinical relevance
Human spermatogonia are target for exploration of adult stem cell characteristics and
potential source for the development of therapeutic applications. Almost 50 years ago, Yves …
potential source for the development of therapeutic applications. Almost 50 years ago, Yves …
Identification of spermatogonial stem cell subsets by morphological analysis and prospective isolation
L Grisanti, I Falciatori, M Grasso, L Dovere, S Fera… - Stem …, 2009 - academic.oup.com
Spermatogenesis is maintained by a pool of spermatogonial stem cells (SSCs). Analyses of
the molecular profile of SSCs have revealed the existence of subsets, indicating that the …
the molecular profile of SSCs have revealed the existence of subsets, indicating that the …
Molecular dissection of the male germ cell lineage identifies putative spermatogonial stem cells in rhesus macaques
BP Hermann, M Sukhwani, DR Simorangkir… - Human …, 2009 - academic.oup.com
BACKGROUND The spermatogonial stem cell (SSC) pool in the testes of non-human
primates is poorly defined. METHODS To begin characterizing SSCs in rhesus macaque …
primates is poorly defined. METHODS To begin characterizing SSCs in rhesus macaque …