Schizophrenia is a highly heritable psychiatric disorder linked to a large number of risk
genes. The function of these genes in disease etiology is not fully understood but pathway …

Background Evidence from genetic association studies implicate genes involved in neural
migration associated with schizophrenia risk. Neural stem/progenitor cell cultures …

Cell migration is critical for brain development and linked to several neurodevelopmental
disorders, including schizophrenia. We have shown previously that cell migration is …

Schizophrenia is a complex neurodevelopmental disorder with high rate of morbidity and
mortality. While the heritability rate is high, the precise etiology is still unknown. Although …

Schizophrenia (SCZ) is a complex neurodevelopmental disorder characterized by the
manifestation of psychiatric symptoms in early adulthood. While many research avenues into …

Molecular and functional abnormalities of astrocytes have been implicated in the etiology
and pathogenesis of schizophrenia (SCZ). In this study, we examined the proteome …

A subgroup of schizophrenia cases with elevated inflammation have reduced neurogenesis
markers and increased macrophage density in the human subependymal zone (SEZ; also …

Schizophrenia is a severe psychiatric disorder with multi-factorial characteristics. A number
of findings have shown disrupted synaptic connectivity in schizophrenia patients and …

In recent years evidence has accumulated that the activity of the signaling cascades of
Neuregulin-1, Wnt, TGF-β, BDNF-p75 and DISC1 is different between control subjects and …

Neuropathological and brain imaging studies suggest that schizophrenia may result from
neurodevelopmental defects. Cytoarchitectural studies indicate cellular abnormalities …