[PDF][PDF] Molecular choreography of acute exercise

K Contrepois, S Wu, KJ Moneghetti, D Hornburg… - Cell, 2020 - cell.com
Acute physical activity leads to several changes in metabolic, cardiovascular, and immune
pathways. Although studies have examined selected changes in these pathways, the system …

[PDF][PDF] Plasma metabolome profiling of resistance exercise and endurance exercise in humans

T Morville, RE Sahl, T Moritz, JW Helge… - Cell reports, 2020 - cell.com
The mechanisms by which exercise benefits human health remain incompletely understood.
With the emergence of omics techniques, mapping of the molecular response to exercise is …

[HTML][HTML] Temporal dynamics of the multi-omic response to endurance exercise training

MoTrPAC Study Group Primary authors, D Amar… - Nature, 2024 - nature.com
Regular exercise promotes whole-body health and prevents disease, but the underlying
molecular mechanisms are incompletely understood,–. Here, the Molecular Transducers of …

Metabolic architecture of acute exercise response in middle-aged adults in the community

M Nayor, RV Shah, PE Miller, JB Blodgett, M Tanguay… - Circulation, 2020 - Am Heart Assoc
Background: Whereas regular exercise is associated with lower risk of cardiovascular
disease and mortality, mechanisms of exercise-mediated health benefits remain less clear …

[HTML][HTML] Metabolomics and lipidomics: expanding the molecular landscape of exercise biology

MR Belhaj, NG Lawler, NJ Hoffman - Metabolites, 2021 - mdpi.com
Dynamic changes in circulating and tissue metabolites and lipids occur in response to
exercise-induced cellular and whole-body energy demands to maintain metabolic …

[HTML][HTML] Exercise training response heterogeneity: physiological and molecular insights

LM Sparks - Diabetologia, 2017 - Springer
The overall beneficial effects of exercise are well studied, but why some people do not
respond favourably to exercise is less understood. The National Institutes of Health …

[PDF][PDF] Molecular transducers of physical activity consortium (MoTrPAC): mapping the dynamic responses to exercise

JA Sanford, CD Nogiec, ME Lindholm, JN Adkins… - Cell, 2020 - cell.com
Exercise provides a robust physiological stimulus that evokes cross-talk among multiple
tissues that when repeated regularly (ie, training) improves physiological capacity, benefits …

[PDF][PDF] Understanding the cellular and molecular mechanisms of physical activity-induced health benefits

PD Neufer, MM Bamman, DM Muoio, C Bouchard… - Cell metabolism, 2015 - cell.com
The beneficial effects of physical activity (PA) are well documented, yet the mechanisms by
which PA prevents disease and improves health outcomes are poorly understood. To …

Metabolic signatures of exercise in human plasma

GD Lewis, L Farrell, MJ Wood, M Martinovic… - Science translational …, 2010 - science.org
Exercise provides numerous salutary effects, but our understanding of how these occur is
limited. To gain a clearer picture of exercise-induced metabolic responses, we have …

[PDF][PDF] Atlas of exercise metabolism reveals time-dependent signatures of metabolic homeostasis

S Sato, KA Dyar, JT Treebak, SL Jepsen, AM Ehrlich… - Cell Metabolism, 2022 - cell.com
Tissue sensitivity and response to exercise vary according to the time of day and alignment
of circadian clocks, but the optimal exercise time to elicit a desired metabolic outcome is not …