The X-ray structure of the superantigen staphylococcal enterotoxin H (SEH) has been
determined at 1.69 Å resolution. In this paper we present two structures of zinc-free SEH …

Staphylococcal enterotoxins are prototype superantigens characterized by their ability to
bind to major histocompatibility complex (MHC) class II molecules and subsequently activate …

Staphylococcal enterotoxin B is a member of a family of toxins known as superantigens that
activate a large number of T-cells (up to 20%) by cross-linking MHC class II molecules with T …

Superantigens form complexes with major histocompatibility complex (MHC) class II
molecules and T-cell receptors resulting in extremely strong immunostimulatory properties …

The three‐dimensional structure of a bacterial superantigen, Staphylococcus aureus
enterotoxin H (SEH), bound to human major histocompatibility complex (MHC) class II (HLA …

The previously determined crystal structure of the superantigen staphylococcal enterotoxin
C2 (SEC2) showed binding of a single zinc ion located between the N-and C-terminal …

Bacterial superantigens, including the staphylococcal enterotoxins, are the most potent
activators of T cells known and have been suggested as a causative factor in Gram‐positive …

Background: Staphylococcus aureus enterotoxin C2 (SEC2) belongs to a family of proteins,
termed 'superantigens', that form complexes with class II MHC molecules enabling them to …

Sir–The crystal structure of the superantigen staphylococcal enterotoxin B has recently been
published". On the basis of sequence homology and conserved amino-acid positions, a …

Superantigens are bacterial or viral proteins that elicit massive T cell activation through
simultaneous binding to major histocompatibility complex (MHC) class II and T cell …