[HTML][HTML] Dyslexia candidate gene and ciliary gene expression dynamics during human neuronal differentiation

A Bieder, M Yoshihara, S Katayama, K Krjutškov… - Molecular …, 2020 - Springer
Developmental dyslexia (DD) is a neurodevelopmental condition with complex genetic
mechanisms. A number of candidate genes have been identified, some of which are linked …

[HTML][HTML] Ciliary dyslexia candidate genes DYX1C1 and DCDC2 are regulated by Regulatory Factor X (RFX) transcription factors through X-box promoter motifs

K Tammimies, A Bieder, G Lauter… - The FASEB …, 2016 - ncbi.nlm.nih.gov
Abstract DYX1C1, DCDC2, and KIAA0319 are three of the most replicated dyslexia
candidate genes (DCGs). Recently, these DCGs were implicated in functions at the cilium …

[HTML][HTML] Genetic and protein interaction studies between the ciliary dyslexia candidate genes DYX1C1 and DCDC2

A Bieder, G Chandrasekar, A Wason… - BMC Molecular and Cell …, 2023 - Springer
Abstract Background DYX1C1 (DNAAF4) and DCDC2 are two of the most replicated
dyslexia candidate genes in genetic studies. They both have demonstrated roles in neuronal …

[HTML][HTML] Dyslexia associated gene KIAA0319 regulates cell cycle during human neuroepithelial cell development

S Paniagua, B Cakir, Y Hu, FR Kiral… - Frontiers in Cell and …, 2022 - frontiersin.org
Dyslexia, also known as reading disability, is defined as difficulty processing written
language in individuals with normal intellectual capacity and educational opportunity. The …

[HTML][HTML] The Zebrafish Orthologue of the Dyslexia Candidate Gene DYX1C1 Is Essential for Cilia Growth and Function

G Chandrasekar, L Vesterlund, K Hultenby… - PloS one, 2013 - journals.plos.org
DYX1C1, a susceptibility gene for dyslexia, encodes a tetratricopeptide repeat domain
containing protein that has been implicated in neuronal migration in rodent models. The …

Dyslexia‐Related Hearing Loss Occurs Mainly through the Abnormal Spontaneous Electrical Activity of Spiral Ganglion Neurons

G Hong, X Fu, X Chen, L Zhang, X Han… - Advanced …, 2023 - Wiley Online Library
Dyslexia is a reading and spelling disorder due to neurodevelopmental abnormalities and is
occasionally found to be accompanied by hearing loss, but the reason for the associated …

[HTML][HTML] Increased expression of the dyslexia candidate gene DCDC2 affects length and signaling of primary cilia in neurons

S Massinen, ME Hokkanen, H Matsson, K Tammimies… - PloS one, 2011 - journals.plos.org
DCDC2 is one of the candidate susceptibility genes for dyslexia. It belongs to the
superfamily of doublecortin domain containing proteins that bind to microtubules, and it has …

The effects of embryonic knockdown of the candidate dyslexia susceptibility gene homologue Dyx1c1 on the distribution of GABAergic neurons in the cerebral cortex

TA Currier, MA Etchegaray, JL Haight, AM Galaburda… - Neuroscience, 2011 - Elsevier
Developmental dyslexia is a language-based learning disability, and a number of candidate
dyslexia susceptibility genes have been identified, including DYX1C1, KIAA0319, and …

A candidate gene for developmental dyslexia encodes a nuclear tetratricopeptide repeat domain protein dynamically regulated in brain

M Taipale, N Kaminen… - Proceedings of the …, 2003 - National Acad Sciences
Approximately 3–10% of people have specific difficulties in reading, despite adequate
intelligence, education, and social environment. We report here the characterization of a …

[HTML][HTML] Normal radial migration and lamination are maintained in dyslexia-susceptibility candidate gene homolog Kiaa0319 knockout mice

I Martinez-Garay, LG Guidi, ZG Holloway… - Brain Structure and …, 2017 - Springer
Developmental dyslexia is a common disorder with a strong genetic component, but the
underlying molecular mechanisms are still unknown. Several candidate dyslexia …