An insulin bolus advisor for type 1 diabetes using deep reinforcement learning

T Zhu, K Li, L Kuang, P Herrero, P Georgiou - Sensors, 2020 - mdpi.com
(1) Background: People living with type 1 diabetes (T1D) require self-management to
maintain blood glucose (BG) levels in a therapeutic range through the delivery of exogenous …

Reinforcement learning for blood glucose control: Challenges and opportunities

I Fox, J Wiens - 2019 - openreview.net
Individuals with type 1 diabetes (T1D) lack the ability to produce the insulin their bodies
need. As a result, they must continually make decisions about how much insulin to self …

Optimized glycemic control of type 2 diabetes with reinforcement learning: a proof-of-concept trial

G Wang, X Liu, Z Ying, G Yang, Z Chen, Z Liu… - Nature Medicine, 2023 - nature.com
The personalized titration and optimization of insulin regimens for treatment of type 2
diabetes (T2D) are resource-demanding healthcare tasks. Here we propose a model-based …

A blood glucose control framework based on reinforcement learning with safety and interpretability: In silico validation

MH Lim, WH Lee, B Jeon, S Kim - IEEE Access, 2021 - ieeexplore.ieee.org
Controlling blood glucose levels in diabetic patients is important for managing their health
and quality of life. Several algorithms based on model predictive control and reinforcement …

A personalized and adaptive insulin bolus calculator based on double deep q-learning to improve type 1 diabetes management

G Noaro, T Zhu, G Cappon… - IEEE Journal of …, 2023 - ieeexplore.ieee.org
Mealtime insulin dosing is a major challenge for people living with type 1 diabetes (T1D).
This task is typically performed using a standard formula that, despite containing some …

Deep reinforcement learning for closed-loop blood glucose control

I Fox, J Lee, R Pop-Busui… - Machine Learning for …, 2020 - proceedings.mlr.press
People with type 1 diabetes (T1D) lack the ability to produce the insulin their bodies need.
As a result, they must continually make decisions about how much insulin to self-administer …

Offline deep reinforcement learning and off-policy evaluation for personalized basal insulin control in type 1 diabetes

T Zhu, K Li, P Georgiou - IEEE Journal of Biomedical and …, 2023 - ieeexplore.ieee.org
Recent advancements in hybrid closed-loop systems, also known as the artificial pancreas
(AP), have been shown to optimize glucose control and reduce the self-management …

Evaluation of blood glucose level control in type 1 diabetic patients using deep reinforcement learning

P Viroonluecha, E Egea-Lopez, J Santa - Plos one, 2022 - journals.plos.org
Diabetes mellitus is a disease associated with abnormally high levels of blood glucose due
to a lack of insulin. Combining an insulin pump and continuous glucose monitor with a …

Basal Glucose Control in Type 1 Diabetes Using Deep Reinforcement Learning: An In Silico Validation

T Zhu, K Li, P Herrero… - IEEE Journal of Biomedical …, 2020 - ieeexplore.ieee.org
People with Type 1 diabetes (T1D) require regular exogenous infusion of insulin to maintain
their blood glucose concentration in a therapeutically adequate target range. Although the …

Reinforcement learning-based adaptive insulin advisor for individuals with type 1 diabetes patients under multiple daily injections therapy

Q Sun, MV Jankovic… - 2019 41st Annual …, 2019 - ieeexplore.ieee.org
The existing adaptive basal-bolus advisor (ABBA) was further developed to benefit patients
under insulin therapy with multiple daily injections (MDI). Three different in silico …