Living organisms perform and control complex behaviours by using webs of chemical
reactions organized in precise networks. This powerful system concept, which is at the very …

Biological organisms use complex molecular networks to navigate their environment and
regulate their internal state. The development of synthetic systems with similar capabilities …

The realization of artificial biochemical reaction networks with unique functionality is one of
the main challenges for the development of synthetic biology. Due to the reduced number of …

Molecular programming takes advantage of synthetic nucleic acid biochemistry to assemble
networks of reactions, in vitro, with the double goal of better understanding cellular …

In living organisms, the integration of signals from the environment and the molecular
computing leading to a cellular response are orchestrated by Gene Regulatory Networks …

Molecular programming aims to systematically engineer molecular and chemical systems of
autonomous function and ever-increasing complexity. A key goal is to develop embedded …

Deriving from logical and mechanical interactions between DNA strands and complexes,
DNA-based artificial reaction networks (RNs) are attractive for their high programmability, as …

Understanding how biochemical networks lead to large-scale nonequilibrium self-
organization and pattern formation in life is a major challenge, with important implications for …

The construction of synthetic biochemical circuits from simple components illuminates how
complex behaviors can arise in chemistry and builds a foundation for future biological …

Artificial biochemical circuits are likely to play as large a role in biological engineering as
electrical circuits have played in the engineering of electromechanical devices. Toward that …