Recently, there has been an increasing need for tools to simulate cell size regulation due to
important applications in cell proliferation and gene expression. However, implementing the …

Background How small, fast-growing bacteria ensure tight cell-size distributions remains
elusive. High-throughput measurement techniques have propelled efforts to build modeling …

Recent studies describe bacterial division as a jump process triggered when it reaches a
fixed number of stochastic discrete events at a rate depending on the cell-size. This …

Intracellular reaction rates depend on concentrations and hence their levels are often
regulated. However classical models of stochastic gene expression lack a cell size …

Fluctuations in protein numbers (noise) due to inherent stochastic effects in single cells can
have large effects on the dynamic behavior of gene regulatory networks. Although …

A recent burst of dynamic single-cell data makes it possible to characterize the stochastic
dynamics of cell division control in bacteria. Different models were used to propose specific …

Cell-to-cell heterogeneity is driven by stochasticity in intracellular reactions and the
population dynamics. While these sources are usually studied separately, we develop an …

How exponentially growing cells maintain size homeostasis is an important fundamental
problem. Recent single-cell studies in prokaryotes have uncovered the adder principle …

Intracellular reaction rates depend on concentrations and hence their levels are often
regulated. However classical models of stochastic gene expression lack a cell size …

Cell growth and division are stochastic processes that exhibit significant amount of cell-to-
cell variation and randomness. In order to connect single cell division dynamics with overall …