Neurons and neural stem cells are sensitive to their mechanical and topographical
environment, and cell–substrate binding contributes to this sensitivity to activate signaling …

Although many details remain still elusive, it became increasingly evident in recent years
that mechanosensing of microenvironmental biophysical cues and subsequent …

A universal principle of all living cells is the ability to sense and respond to mechanical
stimuli which is essential for many biological processes. Recent efforts have identified …

The brain processes information by transmitting signals through highly connected and
dynamic networks of neurons. Neurons use specific cellular structures, including axons …

Extracellular mechanophysical signals from both static substrate cue and dynamic
mechanical loading have strong potential to regulate cell functions. Most of the studies have …

Analysis of cellular mechanotransduction, the mechanism by which cells convert mechanical
signals into biochemical responses, has focused on identification of critical …

Living cells and tissues experience physical forces and chemical stimuli in the human body.
The process of converting mechanical forces into biochemical activities and gene …

Sensing the mechanical properties of the substrates or the matrix by the cells and the
tissues, the subsequent downstream responses at the cellular, nuclear and epigenetic levels …

In nearly all aspects of biology, forces are a relevant regulator of life's form and function.
More recently, science has established that cells are exquisitely sensitive to forces of varying …

Mechanotransduction-how cells sense physical forces and translate them into biochemical
and biological responses-is a vibrant and rapidly-progressing field, and is important for a …