Simple Summary Preexisting reproductive disorders and perturbed placentation are
proposed to play a role in the development of preeclampsia, a leading hypertensive disorder …

Preeclampsia is a prevalent and potentially devastating disorder of pregnancy.
Characterized by a sudden spike in blood pressure and urinary protein levels, it is …

Background Throughout the course of pregnancy, small maternal spiral arteries that are in
contact with fetal tissue undergo structural remodeling, lose smooth muscle cells, and …

Preeclampsia (PE) is a devastating disorder of pregnancy that classically presents with
maternal hypertension and proteinuria after 20 wk of gestation. In addition to being a leading …

Preeclampsia is a pregnancy-specific condition and a leading cause of maternal and fetal
morbidity and mortality. It is thought to occur due to abnormal placental development or …

The hypertensive pregnancy disorder preeclampsia (PE) is a leading cause of fetal and
maternal morbidity/mortality. Obesity increases the risk to develop PE, presumably via the …

Preeclampsia (PE) is a hypertensive disease of pregnancy that affects up to 10% of
pregnant women in the United States and is a leading cause of maternal and fetal …

Modeling preeclampsia remains difficult due to the nature of the disease and the unique
characteristics of the human placenta. Members of the Hominidae superfamily have a villous …

Preeclampsia (PE), a hypertensive disorder of pregnancy, is a leading cause of maternal
and fetal morbidity and mortality. Although the etiology is unknown, PE is thought to be …

Physiological alterations occur in many organ systems during pregnancy. These changes
are necessary for the adaptation to pregnancy-specific physiological processes in mother …