The vertebrate brain and spinal cord arise from a common precursor, the neural tube, which
forms very early during embryonic development. To shape the forming neural tube, changes …

Neurulation, the process of neural tube formation, is a complex morphogenetic event. In the
mammalian embryo, an understanding of the dynamic nature of neurulation has been …

The neural tube is an important model system of morphogenesis representing the
developmental module of out-of-plane epithelial deformation. As the embryonic precursor of …

Your brain and spinal cord began as a flat sheet, which narrowed, elongated, and rolled up
to form a tube. A new study identifies a key molecular link underlying vertebrate neural tube …

The development of the vertebrate spinal cord involves the formation of the neural tube and
the generation of multiple distinct cell types. The process starts during gastrulation …

The neural tube (NT), the embryonic precursor of the vertebrate brain and spinal cord, is
generated by a complex and highly dynamic morphological process. In mammals, the …

Neurulation is a morphogenetic event par excellence. During this highly choreographed four-
dimensional process, a flat sheet of ectoderm is transformed into an elongated tubular …

Neural tube closure has been studied for many decades, across a range of vertebrates, as a
paradigm of embryonic morphogenesis. Neurulation is of particular interest in view of the …

The embryonic brain and spinal cord initially form through the process of neural tube closure
(NTC). NTC is thought to be highly similar between rodents and humans, and studies of …

The developmental process of neurulation involves a series of coordinated morphological
events, which result in conversion of the flat neural plate into the neural tube, the primordium …