Rationale X-ray velocimetry (XV) has been utilized in preclinical models to assess lung
motion and regional ventilation, though no studies have compared XV-derived physiologic …

To effectively diagnose, monitor and treat respiratory disease clinicians should be able to
accurately assess the spatial distribution of airflow across the fine structure of lung. This …

Background: Standard spirometric assessments of COPD fail to capture regional ventilation
heterogeneity (VH). X-ray velocimetry (XV) has promise as a non-invasive tool to assess VH …

Study objective To evaluate the validity of a state-of-the-art computerized planimetry
technique for estimation of total lung capacity (TLC) from chest radiographs, when applied to …

Lung volumes in supine nonambulatory patients are physiological parameters often difficult
to measure with current techniques (plethysmograph, gas dilution). Existing radiographic …

BACKGROUND--Computerised x-ray planimetry has been advocated as an alternative to
body plethysmography and helium dilution for measuring static lung volumes. The accuracy …

We propose a model to measure both regional ventilation (V˙) and perfusion (Q˙) in which
the regional radiodensity (RD) in the lung during xenon (Xe) washin is a function of regional …

RATIONALE AND OBJECTIVES: Multidetector-row computed tomography (MDCT) has
emerged as a tool for quantitative assessment of parenchymal destruction, air trapping …

X-ray based lung function (XLF) as a planar method uses dramatically less X-ray dose than
computed tomography (CT) but so far lacked the ability to relate its parameters to pulmonary …

The evaluation of airway resistance (Raw) in conscious mice requires both end-expiratory
(Ve) and tidal volumes (Vt)(Lai-Fook SJ and Lai YL. J Appl Physiol 98: 2204–2218, 2005). In …