BACKGROUND: Although inhaled corticosteroids (ICSs) are effective in preventing
deterioration in asthma control, at least half of subjects with mild-to-moderate asthma will …

Background: The role of neutrophils in exacerbations of asthma is poorly understood. We
examined the effect of withdrawal of inhaled corticosteroids on sputum inflammatory indexes …

Background Patients with asthma and elevated blood eosinophils are at increased risk of
severe exacerbations. Management of these patients should consider nonadherence to …

To determine predictors for failed reduction of inhaled corticosteroids (ICS), in 50 subjects
with well-controlled asthma (age 43.7 [18–69]; 22 males) taking a median dose of 1,000 μ g …

BACKGROUND: Although guidelines recommend anti-inflammatory therapy for persistent
asthma, recent studies suggest that 25% to 35% of patients with asthma may not improve …

BACKGROUND: Asthma guidelines recommend reducing the dose of inhaled
corticosteroids after establishing control. OBJECTIVE: To identify predictors of loss of control …

Objectives The impact of inhaled corticosteroids (ICS) on eosinophilic inflammation in
asthma is well established, but their effect in a real-life setting has not been extensively …

Introduction: Systemic corticosteroids (SCS) are effective anti-inflammatory therapies for
patients with severe or persistent asthma. Use of SCS reduces blood eosinophil counts; the …

Background It has been suggested that smoking asthmatics benefit less from corticosteroid
treatment than never-smoking asthmatics. We investigated differences in blood and sputum …

Eosinophilic airway inflammation is one of the hallmarks of asthma. Sputum eosinophilia
has been suggested as a predictor of the response to inhaled corticosteroids in asthma. This …