Transfer of tumor-bearing mice intestinal flora can ameliorate cognition in Alzheimer's disease mice

Z Hang, S Cai, T Lei, X Zhang, Z Xiao… - Journal of …, 2022 - content.iospress.com
Background: Fecal microbiota transplant (FMT) is a potential treatment approach for many
diseases. Alzheimer's disease (AD) and cancer have been proven to have a specific …

Neuroprotective effects of fecal microbiota transplantation in a mouse model of Alzheimer's disease: development of new models and analysis methods/validation of …

RMD Holsinger, S Elangovan - Alzheimer's & Dementia, 2020 - Wiley Online Library
Background The efficacy of fecal microbiota transplantation (FMT) as a therapeutic in
Alzheimer's disease was evaluated in the 5XFAD mouse model. Method We treated sixteen …

Fecal microbiota transplantation derived from Alzheimer's disease mice worsens brain trauma outcomes in wild-type controls

S Soriano, K Curry, Q Wang, E Chow… - International Journal of …, 2022 - mdpi.com
Traumatic brain injury (TBI) causes neuroinflammation and neurodegeneration, both of
which increase the risk and accelerate the progression of Alzheimer's disease (AD). The gut …

Transplantation of gut microbiota derived from Alzheimer's disease mouse model impairs memory function and neurogenesis in C57BL/6 mice

N Kim, SH Jeon, IG Ju, MS Gee, J Do, MS Oh… - Brain, behavior, and …, 2021 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disease that causes memory and cognitive
decline. Although many studies have attempted to clarify the causes of AD occurrence, it is …

Fecal microbiota transplantation decreases amyloid load and improves cognition in Alzheimer's

S Elangovan, TJ Borody, RMD Holsinger - BioRxiv, 2019 - biorxiv.org
The efficacy of fecal microbiota transplantation (FMT) in Alzheimer's disease has yet to be
investigated. Here, we show that FMT is capable of providing neuroprotective effects in two …

Fecal microbiota transplantation alleviated Alzheimer's disease-like pathogenesis in APP/PS1 transgenic mice

J Sun, J Xu, Y Ling, F Wang, T Gong, C Yang… - Translational …, 2019 - nature.com
Alzheimer's disease (AD) is the most common dementia in the elderly. Treatment for AD is
still a difficult task in clinic. AD is associated with abnormal gut microbiota. However, little is …

Application of Dominant Gut Microbiota Promises to Replace Fecal Microbiota Transplantation as a New Treatment for Alzheimer's Disease

M Li, H Yang, C Shao, Y Liu, S Wen, L Tang - Microorganisms, 2023 - mdpi.com
Several studies have confirmed that the pathophysiological progression of Alzheimer's
disease (AD) is closely related to changes in the intestinal microbiota; thus, modifying the …

Fecal microbiota transplantation: A novel strategy for treating Alzheimer's disease

W Xiang, H Xiang, J Wang, Y Jiang, C Pan… - Frontiers in …, 2023 - frontiersin.org
Alzheimer's disease is a common neurological disorder, which has become one of the major
factors affecting human health due to its serious impact on individuals, families and society …

Effect of altered gene expression in lipid metabolism on cognitive improvement in patients with Alzheimer's dementia following fecal microbiota transplantation: a …

JS Kim, H Park, JH Lee, J Shin, B Cha… - Therapeutic …, 2024 - journals.sagepub.com
Background: The brain–gut axis has emerged as a potential target in neurodegenerative
diseases, including dementia, as individuals with dementia exhibit distinct gut microbiota …

Cognitive function improvement after fecal microbiota transplantation in Alzheimer's dementia patient: A case report

SH Park, JH Lee, J Shin, JS Kim, B Cha… - Current Medical …, 2021 - Taylor & Francis
After fecal microbiota transplantation (FMT) to treat Clostridioides difficile infection (CDI),
cognitive improvement is noticeable, suggesting an essential association between the gut …