It has been a quarter century since salicylic acid methyltransferase, the founding member of
the plant SABATH enzyme family, was discovered. From making methyl benzoate to …

Evolutionary mechanisms of substrate specificities of enzyme families remain poorly
understood. Plant SABATH methyltransferases catalyze methylation of the carboxyl group of …

Next-generation sequencing has resulted in an explosion of available data, much of which
remains unstudied in terms of biochemical function; yet, experimental characterization of …

Known members of the plant SABATH family of methyltransferases have important biological
functions by methylating hormones, signalling molecules and other metabolites. While all …

Known SABATH methyltransferases, all of which were identified from seed plants, catalyze
methylation of either the carboxyl group of a variety of low molecular weight metabolites or …

In plants, one of the most common modifications of secondary metabolites is methylation
catalyzed by various methyltransferases. Recently, a new class of methyltransferases, the …

Abstract Indole-3-acetic acid (IAA), gibberellins (GAs), salicylic acid (SA) and jasmonic acid
(JA) exist in methyl ester forms in plants in addition to their free acid forms. The enzymes that …

SABATH MTs are found only in the plant kingdom, and they also do not display significant
sequence similarity to other known plant MTs. However, they share several physical …

We used a combined evolutionary and experimental approach to better understand enzyme
functional divergence within the SABATH gene family of methyltransferases (MTs). These …

The plant SABATH protein family encompasses a group of related small-molecule
methyltransferases (MTs) that catalyze the S-adenosyl-l-methionine-dependent methylation …