Molecular epidemiology of HIV-1 in Eastern Europe and Russia

MAA van de Klundert, A Antonova, G Di Teodoro… - Viruses, 2022 - mdpi.com
The HIV epidemic in Eastern Europe and Russia is large and not well-controlled. To
describe the more recent molecular epidemiology of HIV-1, transmitted drug resistance, and …

Molecular epidemiology of the HIV-1 Subtype B sub-epidemic in Bulgaria

I Alexiev, E M. Campbell, S Knyazev, Y Pan… - Viruses, 2020 - mdpi.com
HIV-1 subtype B is the predominant strain in Bulgaria, yet little is known about the molecular
epidemiology of these infections, including its origin and transmissibility. We used a …

HIV-1 integrase resistance among antiretroviral treatment naive and experienced patients from Northwestern Poland

M Parczewski, D Bander, A Urbańska… - BMC Infectious …, 2012 - Springer
Background HIV integrase inhibitor use is limited by low genetic barrier to resistance and
possible cross-resistance among representatives of this class of antiretrovirals. The aim of …

Characterization of integrase region polymorphisms in HIV type 1 CRF06_cpx viruses in treatment-naive patients in Estonia

R Avi, K Huik, M Sadam, T Karki, T Krispin… - AIDS research and …, 2010 - liebertpub.com
Natural polymorphisms of HIV-1, often associated with drug resistance, are widely described
in protease and reverse transcriptase regions but data on their presence in the integrase …

HIV-1 Genetic Diversity in Recently Diagnosed Infections in Moscow: Predominance of AFSU, Frequent Branching in Clusters, and Circulation of the Iberian Subtype …

E Karamov, K Epremyan, A Siniavin… - AIDS Research and …, 2018 - liebertpub.com
HIV-1 protease-reverse transcriptase sequences from 62 HIV-1-infected individuals recently
diagnosed in Moscow were analyzed. Subtype A former Soviet Union (FSU)(AFSU) variant …

Genetic features of HIV-1 integrase sub-subtype A6 predominant in Russia and predicted susceptibility to INSTIs

A Kirichenko, I Lapovok, P Baryshev… - Viruses, 2020 - mdpi.com
The increasing use of the integrase strand transfer inhibitor (INSTI) class for the treatment of
HIV-infection has pointed to the importance of analyzing the features of HIV-1 subtypes for …

Temporal trends in the HIV‐1 epidemic in Russia: Predominance of subtype A

AF Bobkov, EV Kazennova, LM Selimova… - Journal of medical …, 2004 - Wiley Online Library
Abstract During the period 1996–1997, three highly homogeneous variants of HIV‐1 were
identified, circulating among injecting drug users (IDUs) in the former Soviet Union …

Differences in the integrase and reverse transcriptase transmitted resistance patterns in Northern Poland

M Parczewski, M Leszczyszyn-Pynka… - Infection, Genetics and …, 2017 - Elsevier
Introduction With the widespread introduction of the integrase (In) inhibitors into clinical
practice, transmission of drug resistance to this class of antiretroviral medications may …

Absence of primary integrase resistance mutations in HIV type 1-infected patients in Venezuela

HR Rangel, D Garzaro, R Fabbro… - AIDS research and …, 2010 - liebertpub.com
The preexistence of mutations to integrase inhibitors in HIV-1-infected Venezuelan patients
was evaluated. The integrase region of the HIV-1 genome was amplified by nested-PCR …

The HIV type 1 epidemic in Belarus: predominance of Eastern European subtype A strains and circulation of subtype B viruses

NV Lazouskaya, VF Eremin, KW Adema… - AIDS Research & …, 2005 - liebertpub.com
To study the molecular epidemiology of HIV-1 in Belarus, where the rapid spread of HIV-1
has been registered since 1996, we obtained HIV-1 sequences from 30 individuals living in …