Due to the poor ability of self-repair and regeneration, articular cartilage and subchondral
bone defects and degradation are still a big problem nowadays. The aim of the present …

The aim of this study is to fabricate and test a 3D-printed PCL scaffold incorporating IGF-1-
releasing PLGA nanoparticles for cartilage tissue engineering. IGF-1 loaded PLGA …

Insulin is considered to be a classical central regulator of energy homeostasis. Recently, the
effect of insulin on bone has gained a lot of attention, but little attention has been paid to the …

Insulin is widely considered as a classical hormone and drug in maintaining energy and
glucose homeostasis. Recently, insulin has been increasingly recognized as an …

An ideal scaffold for bone tissue engineering should have chondroinductive, biodegradable,
and biocompatible properties, as well as the ability to absorb and slowly release the …

As a synthetic polypeptide water-soluble poly (l-glutamic acid)(PLGA) was designed to
fabricate scaffolds for cartilage tissue engineering. Chitosan (CHI) has been employed as a …

The development of tissue engineering in the field of orthopedic surgery is booming. Two
fields of research in particular have emerged: approaches for tailoring the surface properties …

Osteochondral tissue engineering is challenged by the difficulty in the regeneration of
hyaline cartilage and the simultaneous regeneration of subchondral bone. In the present …

Recently, tissue engineering has become one of the most important approaches in medical
research for the treatment of injuries and lesions. In the present study, poly (l‐lactide) acid …

This study aims to prepare biphasic osteochondral scaffolds based on seamless joining of
sintered polymer and polymer/ceramic microspheres for co-culture of chondrocytes and …