Treatment of Epstein-Barr virus-related hemophagocytic lymphohistiocytosis (EBV-HLH); update 2010

S Imashuku - Journal of pediatric hematology/oncology, 2011 - journals.lww.com
The clinical features of Epstein-Barr virus-related hemophagocytic lymphohistiocytosis (EBV-
HLH) vary significantly, from mild to severe, at the time of the treatment decision. There are …

Treatment choice of immunotherapy or further chemotherapy for Epstein–Barr virus‐associated hemophagocytic lymphohistiocytosis

A Shiraishi, S Ohga, T Doi, M Ishimura… - Pediatric blood & …, 2012 - Wiley Online Library
Abstract Background Epstein–Barr virus‐associated hemophagocytic lymphohistiocytosis
(EBV‐HLH) leads to an aggressive and often fatal course without appropriate treatment …

Spontaneous resolution of Epstein–Barr virus‐associated hemophagocytic lymphohistiocytosis

B Belyea, A Hinson, C Moran, E Hwang… - Pediatric blood & …, 2010 - Wiley Online Library
Secondary hemophagocytic lymphohistiocytosis (sHLH) is a reactive, proliferative disorder
of the immune system resulting in lymphohistiocytic proliferation, hemophagocytosis, and …

Treatment of Epstein‐Barr virus‐associated hemophagocytic lymphohistiocytosis (EBV‐HLH) in young adults: A report from the HLH studyl center

S Imashuku, K Kuriyama, R Sakai… - Medical and …, 2003 - Wiley Online Library
Abstract Background Epstein‐Barr virus‐associated hemophagocytic lymphohistiocytosis
(EBV‐HLH), also known as EBV‐associated hemophagocytic syndrome, develops mostly in …

Effective control of Epstein-Barr Virus–related hemophagocytic lymphohistiocytosis with immunochemotherapy

S Imashuku, S Hibi, T Ohara, A Iwai… - Blood, The Journal …, 1999 - ashpublications.org
The familial form of hemophagocytic lymphohistiocytosis (HLH) is a lethal disorder. Although
the prognosis for Epstein-Barr virus–associated HLH (EBV-HLH) remains uncertain …

Longitudinal follow-up of patients with Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis

S Imashuku, T Teramura, H Tauchi, Y Ishida… - …, 2004 - haematologica.org
BACKGROUND AND OBJECTIVES: Although immunochemotherapy has been reported to
be an effective initial treatment for patients with Epstein-Barr virus-associated …

Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis in adults and adolescents—a life-threatening disease: analysis of 133 cases from a single center

W Lai, Y Wang, J Wang, L Wu, Z Jin, Z Wang - Hematology, 2018 - Taylor & Francis
ABSTRACT Objectives: Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis
is the most common type of infection-associated HLH. Previous studies were focused on …

Prognostic factors of Epstein–Barr virus‐associated hemophagocytic lymphohistiocytosis in children: Report of the Japan Histiocytosis Study Group

K Kogawa, H Sato, T Asano, S Ohga… - Pediatric blood & …, 2014 - Wiley Online Library
Background Despite several advances in the treatment of Epstein–Barr virus (EBV) in recent
years, patients with Epstein–Barr virus‐associated hemophagocytic lymphohistiocytosis …

Clinical features and treatment strategies of Epstein–Barr virus-associated hemophagocytic lymphohistiocytosis

S Imashuku - Critical reviews in oncology/hematology, 2002 - Elsevier
Epstein–Barr virus (EBV) is the major triggering factor producing hemophagocytic syndrome
or hemophagocytic lymphohistiocytosis (HLH). In this review, diagnostic problems, clinical …

Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis: a retrospective study of 78 pediatric cases in mainland of China

Y Jin, Z XIE, S Yang, G Lu, K SHEN - Chinese medical journal, 2010 - mednexus.org
Background The clinical characteristics of Epstein-Barr virus-associated hemophagocytic
lymphohistiocytosis (EBV-HLH) are largely unreported in the pediatric patients in mainland …