Immunological markers, prognostic factors and challenges following curative treatments for hepatocellular carcinoma

SK Lee, SW Lee, JW Jang, SH Bae, JY Choi… - International Journal of …, 2021 - mdpi.com
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related mortalities
worldwide. Patients with early-stage HCC are eligible for curative treatments, such as …

Impact and novel perspective of immune checkpoint inhibitors in patients with early and intermediate stage HCC

L Marzi, A Mega, S Gitto, F Pelizzaro, A Seeber… - Cancers, 2022 - mdpi.com
Simple Summary The prognostic evaluation and therapeutic management of
hepatocarcinoma (HCC) is based on the Barcelona Liver Cancer Clinic (BCLC). In the past …

[HTML][HTML] Prognostic role of immune cells in hepatocellular carcinoma

M Sachdeva, SK Arora - EXCLI journal, 2020 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC), with rising incidence rates, is the most commonly
occurring malignancy of the liver that exerts a heavy disease burden particularly in …

[HTML][HTML] Hepatocellular carcinoma: Mechanisms of progression and immunotherapy

Y Jiang, QJ Han, J Zhang - World journal of gastroenterology, 2019 - ncbi.nlm.nih.gov
Liver cancer is one of the most common malignancies, and various pathogenic factors can
lead to its occurrence and development. Among all primary liver cancers, hepatocellular …

Immunological microenvironment of hepatocellular carcinoma and its clinical implication

N Nishida, M Kudo - Oncology, 2017 - karger.com
Despite recent advances in the treatment of hepatocellular carcinoma (HCC), the prognosis
of patients with advanced stage of disease remains unfavorable. Several immune therapies …

Current Evidence for Immune Checkpoint Inhibition in Advanced Hepatocellular Carcinoma

V Foy, MG McNamara, JW Valle, A Lamarca… - Current …, 2023 - mdpi.com
The treatment of advanced unresectable HCC (aHCC) remains a clinical challenge, with
limited therapeutic options and poor prognosis. The results of IMbrave150 and HIMALAYA …

[HTML][HTML] Biochemical predictors of response to immune checkpoint inhibitors in unresectable hepatocellular carcinoma

A Rizzo, G Brandi - Cancer treatment and research communications, 2021 - Elsevier
Hepatocellular carcinoma (HCC) represents the most commonly diagnosed liver cancer
worldwide, and the overall survival of patients with unresectable disease is poor. In the last …

Predictive biomarkers for checkpoint inhibitor-based immunotherapy in hepatocellular carcinoma: where do we stand?

A Rizzo, AD Ricci, A Di Federico, G Frega… - Frontiers in …, 2021 - frontiersin.org
Hepatocellular carcinoma (HCC) remains the sixth most commonly diagnosed malignancy
worldwide, still representing an important cause of cancer-related death. Over the next few …

Immune checkpoint inhibitors in hepatocellular carcinoma: A review of current clinical trials

AC Gamboa, DA Kooby, SK Maithel… - Journal of Surgical …, 2024 - Wiley Online Library
Hepatocellular carcinoma (HCC) is the most common primary liver cancer with a poor
prognosis due to advanced disease presentation or recurrence despite curative‐intent …

Rationale of immunotherapy in hepatocellular carcinoma and its potential biomarkers

D Tai, SP Choo, V Chew - Cancers, 2019 - mdpi.com
Hepatocellular carcinoma (HCC), the most common type of liver cancer, is derived mostly
from a background of chronic inflammation. Multiple immunotherapeutic strategies have …