Ferroptosis and its emerging roles in cardiovascular diseases

N Li, W Jiang, W Wang, R Xiong, X Wu… - Pharmacological Research, 2021 - Elsevier
Ferroptosis is a new form of regulated cell death (RCD) driven by iron-dependent lipid
peroxidation, which is morphologically and mechanistically distinct from other forms of RCD …

[HTML][HTML] Emerging roles of ferroptosis in cardiovascular diseases

K Wang, XZ Chen, YH Wang, XL Cheng, Y Zhao… - Cell death …, 2022 - nature.com
The mechanism of cardiovascular diseases (CVDs) is complex and threatens human health.
Cardiomyocyte death is an important participant in the pathophysiological basis of CVDs …

[HTML][HTML] Molecular mechanisms of ferroptosis and relevance to cardiovascular disease

LH Xie, N Fefelova, SH Pamarthi, JK Gwathmey - Cells, 2022 - mdpi.com
Ferroptosis has recently been demonstrated to be a novel regulated non-apoptotic cell
death characterized by iron-dependence and the accumulation of lipid peroxidation that …

[HTML][HTML] The link between ferroptosis and cardiovascular diseases: a novel target for treatment

H Hu, Y Chen, L Jing, C Zhai, L Shen - Frontiers in Cardiovascular …, 2021 - frontiersin.org
Ferroptosis is an iron-dependent cell death, which is characterized by iron overload and
lipid peroxidation. Ferroptosis is distinct from apoptosis, necroptosis, autophagy, and other …

[HTML][HTML] New insights into the role of ferroptosis in cardiovascular diseases

AM Fratta Pasini, C Stranieri, F Busti, EG Di Leo… - Cells, 2023 - mdpi.com
Cardiovascular diseases (CVDs) are the principal cause of disease burden and death
worldwide. Ferroptosis is a new form of regulated cell death mainly characterized by altered …

[HTML][HTML] Targeting ferroptosis to treat cardiovascular diseases: a new continent to be explored

F Huang, R Yang, Z Xiao, Y Xie, X Lin, P Zhu… - Frontiers in Cell and …, 2021 - frontiersin.org
Cardiovascular diseases, including cardiomyopathy, myocardial infarction, myocardial
ischemia/reperfusion injury, heart failure, vascular injury, stroke, and arrhythmia, are …

[HTML][HTML] Roles of ferroptosis in cardiovascular diseases

Y Guo, W Zhang, X Zhou, S Zhao, J Wang… - Frontiers in …, 2022 - frontiersin.org
Ferroptosis is an iron-dependent regulated cell death characterized by lipid peroxidation
and iron overload, which is different from other types of programmed cell death, including …

[HTML][HTML] The role of ferroptosis in cardiovascular disease and its therapeutic significance

Z Chen, Y Yan, C Qi, J Liu, L Li, J Wang - Frontiers in cardiovascular …, 2021 - frontiersin.org
Cardiovascular diseases (CVDs) are the leading cause of deaths worldwide with regulated
cell death playing an important role in cardiac pathophysiology. However, the classical …

[HTML][HTML] The emerging role of ferroptosis in cardiovascular diseases

M Hong, J Rong, X Tao, Y Xu - Frontiers in Pharmacology, 2022 - frontiersin.org
Ferroptosis is one type of programmed cell death discovered in recent years, which is
characterized by iron-dependent lipid peroxidation and participating in iron, lipid and …

[HTML][HTML] Ferroptosis in cardiovascular diseases: current status, challenges, and future perspectives

Y Guo, C Lu, K Hu, C Cai, W Wang - Biomolecules, 2022 - mdpi.com
Cardiovascular diseases (CVDs) are still a major cause of global mortality and disability,
seriously affecting people's lives. Due to the severity and complexity of these diseases, it is …