Background The upper cervical dorsal root ganglia (DRG) are important for the transmission
of sensory information associated with the back of the head and neck, contributing to head …

Background Calcitonin gene-related peptide (CGRP) has a key role in migraine
pathophysiology and is associated with activation of the trigeminovascular system. The …

The neuropeptide calcitonin gene-related peptide (CGRP) is expressed in the trigeminal
ganglia, a key site in craniofacial pain and migraine. CGRP potently activates two receptors …

Objective The trigeminovascular system plays a central role in migraine, a condition in need
of new treatments. The neuropeptide, calcitonin gene‐related peptide (CGRP), is proposed …

Background Amylin is a peptide from the calcitonin gene‐related peptides (CGRP) family
that is expressed by nociceptors. Amylin may modulate pain via a spinal action. Methods …

Amylin is a member of calcitonin or calcitonin gene-related peptide (CGRP) family.
Immunohistochemical study revealed a dense network of amylin-immunoreactive (irAMY) …

Calcitonin gene‐related peptide (CGRP) is a key mediator in primary headaches including
migraine. Animal models of meningeal nociception demonstrate both peripheral and central …

Orofacial pain conditions including temporomandibular disorder (TMD) and migraine are
characterized by peripheral and central sensitization of trigeminal nociceptive neurons. The …

The neuropeptide calcitonin gene-related peptide (CGRP) is implicated in the underlying
pathology of migraine by promoting the development of a sensitized state of primary and …

Primary headaches such as migraine are postulated to involve the activation of sensory
trigeminal pain neurons that innervate intracranial blood vessels and the dura mater. It is …