B cells in primary membranous nephropathy: escape from immune tolerance and implications for patient management

BYF So, DYH Yap, TM Chan - International Journal of Molecular Sciences, 2021 - mdpi.com
Membranous nephropathy (MN) is an important cause of nephrotic syndrome and chronic
kidney disease (CKD) in adults. The pathogenic significance of B cells in MN is increasingly …

[HTML][HTML] B-and T-cell subpopulations in patients with severe idiopathic membranous nephropathy may predict an early response to rituximab

M Rosenzwajg, E Languille, H Debiec, J Hygino… - Kidney international, 2017 - Elsevier
Primary membranous nephropathy (PMN) is characterized by antibodies to the podocyte,
but little is known about B-and T-cell populations and their response to rituximab is …

Idiopathic membranous nephropathy: diagnosis and treatment

FC Fervenza, S Sethi, U Specks - Clinical Journal of the American …, 2008 - journals.lww.com
Idiopathic membranous nephropathy is still the most common glomerular disease
associated with nephrotic syndrome. The greater the proteinuria, the greater the long-term …

[HTML][HTML] Regulatory B cells are reduced and correlate with disease activity in primary membranous nephropathy

R Ramachandran, U Kaundal, N Girimaji… - Kidney International …, 2020 - Elsevier
Introduction Primary membranous nephropathy (PMN) is an autoimmune disease. Both T-
regulatory cells (TREGs) and B-regulatory cells (BREGs) are decreased in patients with …

[HTML][HTML] Novel treatments paradigms: membranous nephropathy

JE Rojas-Rivera, A Ortiz, FC Fervenza - Kidney international reports, 2023 - Elsevier
Primary membranous nephropathy (MN) is a kidney-specific autoimmune glomerular
disease and the leading cause of nephrotic syndrome (NS) in White adults, usually caused …

Unmet challenges in membranous nephropathy

DJ Salant - Current opinion in nephrology and hypertension, 2019 - journals.lww.com
Unmet challenges in membranous nephropathy : Current Opinion in Nephrology and
Hypertension Unmet challenges in membranous nephropathy : Current Opinion in …

Immune system-mediated cellular and molecular mechanisms in idiopathic membranous nephropathy pathogenesis and possible therapeutic targets

R Motavalli, J Etemadi, H Kahroba, A Mehdizadeh… - Life sciences, 2019 - Elsevier
Idiopathic membranous nephropathy (IMN) has recently attracted much attention due to the
development of auto antibodies, anti-phospholipase A2 receptor and anti-thrombospondin …

Immunopathogenesis of membranous nephropathy: an update

H Debiec, P Ronco - Seminars in immunopathology, 2014 - Springer
Membranous nephropathy (MN) is a non-inflammatory organ-specific autoimmune disease
which affects the kidney glomerulus, resulting in the formation of immune deposits on the …

Translational aspects of primary membranous nephropathy

E Hoxha, RAK Stahl - Seminars in Nephrology, 2017 - Elsevier
Membranous nephropathy (MN) in an autoimmune disease caused by binding of circulating
antibodies to podocytic antigens. The search for the responsible target antigens has …

Membranous nephropathy treatment standard

Y Radhakrishnan, L Zand, S Sethi… - Nephrology Dialysis …, 2024 - academic.oup.com
Membranous nephropathy (MN) is characterized by deposition of immune complexes
leading to thickening of glomerular basement membranes. Over time, the understanding of …