Metabolism differs significantly between tumor and normal cells. Metabolic reprogramming
in cancer cells and metabolic interplay in the tumor microenvironment (TME) are important …

Metabolism is a series of life-sustaining chemical reactions in organisms, providing energy
required for cellular processes and building blocks for cellular constituents of proteins, lipids …

Among all the adaptations of cancer cells, their ability to change metabolism from the
oxidative to the glycolytic phenotype is a hallmark called the Warburg effect. Studies on …

Warburg found that tumor cells exhibit high‑level glycolysis, even under aerobic condition,
which is known as the 'Warburg effect'. As systemic changes in the entire metabolic network …

Although the incidence of thyroid cancer is increasing year by year, most patients, especially
those with differentiated thyroid cancer, can usually be cured with surgery, radioactive …

Oncocytic thyroid cancer is characterized by the aberrant accumulation of abnormal
mitochondria in the cytoplasm and a defect in oxidative phosphorylation. We performed …

Thyroid cancer (TC) is the most frequent endocrine tumor with a growing incidence
worldwide. Besides the improvement of diagnosis, TC increasing incidence is probably due …

Background: Energy metabolism is described to be deregulated in cancer, and the Warburg
effect is considered to be a major hallmark. Recently, cellular heterogeneity in tumors and …

Metabolic reprogramming with heterogeneity is a hallmark of cancer and is at the basis of
malignant behaviors. It supports the proliferation and metastasis of tumor cells according to …

The last few decades have witnessed an outstanding advancement in our understanding of
the hallmarks of endocrine cancers. This includes the epithelial to mesenchymal transition …