Dendritic-cell-based therapeutic cancer vaccines
K Palucka, J Banchereau - Immunity, 2013 - cell.com
The past decade has seen tremendous developments in novel cancer therapies through the
targeting of tumor-cell-intrinsic pathways whose activity is linked to genetic alterations and …
targeting of tumor-cell-intrinsic pathways whose activity is linked to genetic alterations and …
Dendritic cell-based therapeutic cancer vaccines: what we have and what we need
P Kalinski, J Urban, R Narang, E Berk… - Future …, 2009 - Taylor & Francis
Therapeutic cancer vaccines rely on the immune system to eliminate tumor cells. In contrast
to chemotherapy or passive (adoptive) immunotherapies with antibodies or ex vivo …
to chemotherapy or passive (adoptive) immunotherapies with antibodies or ex vivo …
Trial watch: Dendritic cell-based interventions for cancer therapy
Dendritic cells (DCs) occupy a central position in the immune system, orchestrating a wide
repertoire of responses that span from the development of self-tolerance to the elicitation of …
repertoire of responses that span from the development of self-tolerance to the elicitation of …
Trial watch: dendritic cell-based anticancer immunotherapy
AD Garg, M Vara Perez, M Schaaf, P Agostinis… - …, 2017 - Taylor & Francis
Dendritic cell (DC)-based vaccines against cancer have been extensively developed over
the past two decades. Typically DC-based cancer immunotherapy entails loading patient …
the past two decades. Typically DC-based cancer immunotherapy entails loading patient …
Trial watch: dendritic cell vaccination for cancer immunotherapy
J Sprooten, J Ceusters, A Coosemans… - …, 2019 - Taylor & Francis
Dendritic-cells (DCs) have received considerable attention as potential targets for the
development of anticancer vaccines. DC-based anticancer vaccination relies on patient …
development of anticancer vaccines. DC-based anticancer vaccination relies on patient …
Cancer immunotherapy by dendritic cells
CJM Melief - Immunity, 2008 - cell.com
Cancerous lesions promote tumor growth, motility, invasion, and angiogenesis via
oncogene-driven immunosuppressive leukocyte infiltrates, mainly myeloid-derived …
oncogene-driven immunosuppressive leukocyte infiltrates, mainly myeloid-derived …
Antitumor dendritic cell–based vaccines: lessons from 20 years of clinical trials and future perspectives
Dendritic cells (DCs) are versatile elements of the immune system and are best known for
their unparalleled ability to initiate and modulate adaptive immune responses. During the …
their unparalleled ability to initiate and modulate adaptive immune responses. During the …
Dendritic cell-based vaccines against cancer: challenges, advances and future opportunities
As the most potent professional antigen presenting cells, dendritic cells (DCs) have the
ability to activate both naive CD4 and CD8 T cells. Recognized for their exceptional ability to …
ability to activate both naive CD4 and CD8 T cells. Recognized for their exceptional ability to …
Dendritic cells: a critical player in cancer therapy?
AK Palucka, H Ueno, J Fay… - Journal of …, 2008 - journals.lww.com
Cancer immunotherapy seeks to mobilize a patient's immune system for therapeutic benefit.
It can be passive, that is, transfer of immune effector cells (T cells) or proteins (antibodies), or …
It can be passive, that is, transfer of immune effector cells (T cells) or proteins (antibodies), or …
Trial watch: Dendritic cell (DC)-based immunotherapy for cancer
Dendritic cell (DC)-based vaccination for cancer treatment has seen considerable
development over recent decades. However, this field is currently in a state of flux toward …
development over recent decades. However, this field is currently in a state of flux toward …