The chemokine system in oncogenic pathways driven by viruses: perspectives for cancer immunotherapy

G Schlecht-Louf, C Deback, F Bachelerie - Cancers, 2022 - mdpi.com
Simple Summary Oncoviruses are viruses with oncogenic potential, responsible for almost
20% of human cancers worldwide. They are from various families, some of which belong to …

Cytokines in oncolytic virotherapy

JG Pol, ST Workenhe, P Konda, S Gujar… - Cytokine & Growth Factor …, 2020 - Elsevier
Tumors represent a hostile environment for the effector cells of cancer immunosurveillance.
Immunosuppressive receptors and soluble or membrane-bound ligands are abundantly …

The chemokine network: a target in cancer biology?

VIF Slettenaar, JL Wilson - Advanced drug delivery reviews, 2006 - Elsevier
Chemokine gradients are central to the movement of cells in both homeostatic and
pathological processes. Most cancers express a complex array of chemokines that influence …

Chemokine-directed tumor microenvironment modulation in cancer immunotherapy

P Bule, SI Aguiar, F Aires-Da-Silva… - International Journal of …, 2021 - mdpi.com
Chemokines are a large family of small chemotactic cytokines that coordinates immune cell
trafficking. In cancer, they have a pivotal role in the migration pattern of immune cells into the …

Tumour-immune cell interactions modulated by chemokines

K Jöhrer, L Pleyer, A Olivier, E Maizner… - Expert opinion on …, 2008 - Taylor & Francis
Background: Chemokines are involved in almost all aspects of tumour establishment and
progression. Objective: This review gives an insight into the complexity of chemokines and …

Chemokines and Chemokine Receptors in Cancer: An Update

NM Elemam, AA Maghazachi - Handbook of Cancer and Immunology, 2023 - Springer
The chemokine family is composed of small chemotactic cytokines and receptors that
mediate the infiltration of various immune cells. According to the position of the cysteine …

[HTML][HTML] Chemokines and chemokine receptors: new targets for cancer immunotherapy

V Mollica Poeta, M Massara, A Capucetti… - Frontiers in …, 2019 - frontiersin.org
Immunotherapy is a clinically validated treatment for many cancers to boost the immune
system against tumor growth and dissemination. Several strategies are used to harness …

Chemokines in the cancer microenvironment and their relevance in cancer immunotherapy

N Nagarsheth, MS Wicha, W Zou - Nature Reviews Immunology, 2017 - nature.com
The tumour microenvironment is the primary location in which tumour cells and the host
immune system interact. Different immune cell subsets are recruited into the tumour …

Role of chemokine systems in cancer and inflammatory diseases

H Li, M Wu, X Zhao - MedComm, 2022 - Wiley Online Library
Chemokines are a large family of small secreted proteins that have fundamental roles in
organ development, normal physiology, and immune responses upon binding to their …

The pros and cons of chemokines in tumor immunology

A Viola, A Sarukhan, V Bronte, B Molon - Trends in immunology, 2012 - cell.com
Innate and adaptive immune cells can intervene during tumor progression at different stages
including initiation, angiogenesis, local spreading and distant metastasis formation. The net …