[HTML][HTML] Ablation of the miRNA cluster 24 has profound effects on extracellular matrix protein abundance in cartilage

VS Georgieva, J Etich, B Bluhm, M Zhu, C Frie… - International Journal of …, 2020 - mdpi.com
MicroRNAs (miRNAs) regulate cartilage differentiation and contribute to the onset and
progression of joint degeneration. These small RNA molecules may affect extracellular …

MiR-26a modulates extracellular matrix homeostasis in cartilage

J Etich, T Holzer, L Pitzler, B Bluhm, B Brachvogel - Matrix Biology, 2015 - Elsevier
MicroRNAs (miRNAs) may represent new therapeutic targets for bone and joint diseases.
We hypothesized that several cartilage-specific proteins are targeted by a single miRNA and …

MicroRNA-181b regulates articular chondrocytes differentiation and cartilage integrity

J Song, M Lee, D Kim, J Han, CH Chun… - … and biophysical research …, 2013 - Elsevier
MicroRNAs are endogenous gene regulators that have been implicated in various
developmental and pathological processes. However, the precise identities and functions of …

[HTML][HTML] Ablation of the miRNA cluster 24 in cartilage and osteoblasts impairs bone remodeling

VS Georgieva, B Bluhm, K Probst, M Zhu, J Heilig… - Scientific Reports, 2022 - nature.com
MicroRNAs (miRNAs) post-transcriptionally regulate cartilage and bone development and
function, however, only few miRNAs have been described to play a role for cartilage to bone …

Novel role of miR‐181a in cartilage metabolism

K Sumiyoshi, S Kubota, T Ohgawara… - Journal of cellular …, 2013 - Wiley Online Library
Micro RNA (miRNA) is a small non‐coding post‐transcriptional RNA regulator that is
involved in a variety of biological events. In order to specify the role of miRNAs in cartilage …

MicroRNA‐140 is expressed in differentiated human articular chondrocytes and modulates interleukin‐1 responses

S Miyaki, T Nakasa, S Otsuki, SP Grogan… - Arthritis & …, 2009 - Wiley Online Library
Objective MicroRNA (miRNA) are a class of noncoding small RNAs that act as negative
regulators of gene expression. MiRNA exhibit tissue‐specific expression patterns, and …

The expression and function of microRNAs in chondrogenesis and osteoarthritis

TE Swingler, G Wheeler, V Carmont… - Arthritis & …, 2012 - Wiley Online Library
Objective To use an in vitro model of chondrogenesis to identify microRNAs (miRNAs) with a
functional role in cartilage homeostasis. Methods The expression of miRNAs was measured …

[HTML][HTML] MicroRNA-337 is associated with chondrogenesis through regulating TGFBR2 expression

N Zhong, J Sun, Z Min, W Zhao, R Zhang… - Osteoarthritis and …, 2012 - Elsevier
OBJECTIVE: MicroRNAs (miRNAs) have been implicated in regulating diverse cellular
pathways and involved in development and inflammation. This study aimed to examine six …

Chondrocyte miRNAs 221 and 483-5p respond to loss of matrix interaction by modulating proliferation and matrix synthesis

M Yang, L Zhang, GJ Gibson - Connective tissue research, 2015 - Taylor & Francis
Aim: The purpose of this study was to identify the microRNAs that regulate the response of
chondrocytes to loss of matrix interaction. Materials and methods: MicroRNA and gene …

MicroRNAs in cartilage development, homeostasis, and disease

F Mirzamohammadi, G Papaioannou… - Current osteoporosis …, 2014 - Springer
Abstract microRNAs (miRNAs) regulate gene expression mainly at the posttranscriptional
level. Many different miRNAs are expressed in chondrocytes, and each individual miRNA …