Neuropsychological Alterations in Patients with Congenital Hypothyroidism Treated with Levothyroxine: Linked Factors and Thyroid Hormone Hyposensitivity

KC Razón-Hernández, N Osnaya-Brizuela… - Journal of Clinical …, 2022 - mdpi.com
Eighty-five percent of the studies of patients with congenital hypothyroidism (CH) treated
with Levothyroxine (L-T4) report neuropsychological sequelae throughout life. In neonates …

Cognitive function in children with idiopathic subclinical hypothyroidism: effects of 2 years of levothyroxine therapy

D Capalbo, S Alfano, M Polizzi… - The Journal of …, 2020 - academic.oup.com
Background Long-term consequences of mild subclinical hypothyroidism (SH) in children
are still unclear, and the need for levothyroxine (L-T4) supplementation remains …

Neuropsychological follow-up in early-treated congenital hypothyroidism: a problem-oriented approach

S Bargagna, G Canepa, C Costagli, D Dinetti… - Thyroid, 2000 - liebertpub.com
Screening programs for congenital hypothyroidism (CH) dramatically improved the
neuropsychological prognosis in affected children. However, mild impairments in cognitive …

Long‐term neuropsychological sequelae of early‐treated congenital hypothyroidism: effects in adolescence

JF Rovet - Acta Paediatrica, 1999 - Wiley Online Library
A cohort of over 100 children with congenital hypothyroidism (CH) detected via newborn
screening was followed regularly throughout childhood and into adolescence. They were …

Neurocognitive function in children with compensated hypothyroidism: lack of short term effects on or off thyroxin

NJ Aijaz, EM Flaherty, T Preston, SS Bracken… - BMC endocrine …, 2006 - Springer
Background Although thyroxin therapy clearly is beneficial to children with frank
hypothyroidism there is little data on the effects of thyroxin in children with compensated or …

Congenital hypothyroidism: a review of current diagnostic and treatment practices in relation to neuropsychologic outcome

J Rovet, D Daneman - Pediatric Drugs, 2003 - Springer
Because thyroid hormone is essential for normal brain development, children born with
congenital hypothyroidism who lack thyroid hormone during a circumscribed period of early …

Congenital hypothyroidism: no adverse effects of high dose thyroxine treatment on adult memory, attention, and behaviour

B Oerbeck, K Sundet, BF Kase… - Archives of disease in …, 2005 - adc.bmj.com
Background: In congenital hypothyroidism (CH) it has been questioned whether high dose
thyroxine replacement therapy has detrimental effects on memory, attention, and behaviour …

Congenital hypothyroidism: an analysis of persisting deficits and associated factors

JF Rovet - Child Neuropsychology, 2002 - Taylor & Francis
Congenital hypothyroidism (CH) is a neonatal disorder that is caused by a prolonged loss of
thyroid hormone, which is essential for early brain development. While CH was once the …

Influence of timing and dose of thyroid hormone replacement on mental, psychomotor, and behavioral development in children with congenital hypothyroidism

JJ Bongers-Schokking… - The Journal of …, 2005 - Elsevier
OBJECTIVES: To evaluate the influence of initial and postinitial treatment factors on
cognitive, psychomotor, and psychological outcome in schoolchildren with congenital …

Long-term effects of L-thyroxine therapy for congenital hypothyroidism

JF Rovet, RM Ehrlich - The Journal of pediatrics, 1995 - Elsevier
Objective: To study the effects of initial and concurrent dose levels of L-thyroxine on ability
and behavior in children with congenital hypothyroidism. Methods: An existing database …