Human papillomaviruses modulate microRNA 145 expression to directly control genome amplification

V Gunasekharan, LA Laimins - Journal of virology, 2013 - Am Soc Microbiol
Human papillomaviruses (HPVs) modulate expression of host microRNAs. Our deep-
sequencing analysis of organotypic raft cultures identified microRNA 145 (miR-145) as a …

Human papillomaviruses modulate expression of microRNA 203 upon epithelial differentiation to control levels of p63 proteins

M Melar-New, LA Laimins - Journal of virology, 2010 - Am Soc Microbiol
Human papillomaviruses (HPV) link their life cycles to epithelial differentiation and induce
productive replication of viral DNA in suprabasal cells. Viral-DNA amplification requires cells …

Modulation of microRNA-mRNA target pairs by human papillomavirus 16 oncoproteins

ME Harden, N Prasad, A Griffiths, K Munger - MBio, 2017 - Am Soc Microbiol
The E6 and E7 proteins are the major oncogenic drivers encoded by high-risk human
papillomaviruses (HPVs). While many aspects of the transforming activities of these proteins …

Human papillomavirus type 16 reduces the expression of microRNA-218 in cervical carcinoma cells

I Martinez, AS Gardiner, KF Board, FA Monzon… - Oncogene, 2008 - nature.com
Human papillomaviruses (HPVs) are involved in the pathogenesis of cancer of the cervix
(CaCx). MicroRNA (miRNA) expression analysis using Ambion (Austin, TX, USA) arrays …

Identification and validation of human papillomavirus encoded microRNAs

K Qian, T Pietilä, M Rönty, F Michon, MJ Frilander… - PLoS …, 2013 - journals.plos.org
We report here identification and validation of the first papillomavirus encoded microRNAs
expressed in human cervical lesions and cell lines. We established small RNA libraries from …

Identification of virus-encoded microRNAs in divergent Papillomaviruses

R Chirayil, RP Kincaid, C Dahlke, CV Kuny… - PLoS …, 2018 - journals.plos.org
MicroRNAs (miRNAs) are small RNAs that regulate diverse biological processes including
multiple aspects of the host-pathogen interface. Consequently, miRNAs are commonly …

Human papillomavirus 16 E5 modulates the expression of host microRNAs

D Greco, N Kivi, K Qian, SK Leivonen, P Auvinen… - PloS one, 2011 - journals.plos.org
Human papillomavirus (HPV) infection is a prerequisite of developing cervical cancer,
approximately half of which are associated with HPV type 16. HPV 16 encodes three …

Two less common human microRNAs miR-875 and miR-3144 target a conserved site of E6 oncogene in most high-risk human papillomavirus subtypes

L Lin, Q Cai, X Zhang, H Zhang, Y Zhong, C Xu… - Protein & …, 2015 - academic.oup.com
Human papillomaviruses (HPVs) including high-risk (HR) and low-risk (LR) subtypes have
distinguishable variation on both genotypes and phenotypes. The co-infection of multiple …

A role for microRNA-155 expression in microenvironment associated to HPV-induced carcinogenesis in K14-HPV16 transgenic mice

I Paiva, RM Gil da Costa, J Ribeiro, H Sousa… - PLoS …, 2015 - journals.plos.org
Human Papillomavirus cause a number of diseases most notably cervical cancer. K14-
HPV16 transgenic mice expressing the HPV16 early genes in squamous epithelial cells …

microRNAs are biomarkers of oncogenic human papillomavirus infections

X Wang, HK Wang, Y Li, M Hafner… - Proceedings of the …, 2014 - National Acad Sciences
Cellular and viral microRNAs (miRNAs) are the transcriptional products of RNA polymerase
II and are regulated by transcriptional factors for their differential expression. The altered …