Radiotherapy modulates tumor cell fate decisions: a review

H Chen, Z Han, Q Luo, Y Wang, Q Li, L Zhou, H Zuo - Radiation Oncology, 2022 - Springer
Cancer has always been a worldwide problem, and the application of radiotherapy has
greatly improved the survival rate of cancer patients. Radiotherapy can modulate multiple …

[HTML][HTML] The scheme, and regulative mechanism of pyroptosis, ferroptosis, and necroptosis in radiation injury

J Ning, L Chen, Y Zeng, G Xiao, W Tian… - … Journal of Biological …, 2024 - ncbi.nlm.nih.gov
Radiotherapy (RT) stands as the primary treatment for tumors, but it inevitably causes
damage to normal cells. Consequently, radiation injury is a crucial consideration for …

Ferroptosis, necroptosis, and pyroptosis in cancer: Crucial cell death types in radiotherapy and post-radiotherapy immune activation

Y Wang, Y Wang, J Pan, L Gan, J Xue - Radiotherapy and Oncology, 2023 - Elsevier
Tumor cell death and antitumor immune activation induced by radiotherapy are extensively
well-studied. While radiotherapy is believed to mainly induce tumor cell necrosis and …

Basis of cell kill following clinical radiotherapy

M Sluyser, O Faulhaber, RG Bristow - Application of apoptosis to cancer …, 2005 - Springer
Over one half of cancer patients are treated radiotherapy. Technological advances in
radiation targeting and concurrent chemotherapy continue to improve clinical radiotherapy …

Cell death–stimulated cell proliferation: A tissue regeneration mechanism usurped by tumors during radiotherapy

MA Zimmerman, Q Huang, F Li, X Liu, CY Li - Seminars in radiation …, 2013 - Elsevier
The death of all the cancer cells in a tumor is the ultimate goal of cancer therapy. Therefore,
much of the current effort in cancer research is focused on activating cellular machinery that …

[HTML][HTML] Molecular mechanisms of radiation-induced cancer cell death: a primer

J Sia, R Szmyd, E Hau, HE Gee - Frontiers in cell and developmental …, 2020 - frontiersin.org
Radiation therapy (RT) is responsible for at least 40% of cancer cures, however treatment
resistance remains a clinical problem. There have been recent advances in understanding …

[HTML][HTML] The role of radiation-induced apoptosis as a determinant of tumor responses to radiation therapy

BA Rupnow, SJ Knox - Apoptosis, 1999 - Springer
Ionizing radiation is an effective means of killing tumor cells. Approximately 50% of all
American cancer patients are treated with radiotherapy at some time during the course of …

Apoptosis in radiation therapy: a double-edged sword

EK Balcer-Kubiczek - Experimental oncology, 2012 - dspace.nbuv.gov.ua
Radiation therapy achieves its therapeutic effects by inducing apoptosis and non-apoptotic
cell death. The aim of this focused review is to highlight the aspects of the cell death …

Radiation-induced cell death and its mechanisms

Y Jiao, F Cao, H Liu - Health physics, 2022 - journals.lww.com
With rapid technical advances, ionizing radiation has been put into wider application in
ordinary living, with the worst cytological effect on the human body being cell death …

Dark side of cytotoxic therapy: Chemoradiation-induced cell death and tumor repopulation

M Jiang, D Gu, J Dai, Q Huang, L Tian - Trends in cancer, 2020 - cell.com
Accelerated tumor repopulation following chemoradiation is often observed in the clinic, but
the underlying mechanisms remain unclear. In recent years, dying cells caused by …