Combating tigecycline resistant Acinetobacter baumannii: A leap forward towards multi-epitope based vaccine discovery
Global emergence of Tigecycline resistant Acinetobacter baumannii (TRAB) is on the
horizon and poses a very serious threat to human health. There is a pressing demand for …
horizon and poses a very serious threat to human health. There is a pressing demand for …
Promising Acinetobacter baumannii Vaccine Candidates and Drug Targets in Recent Years
In parallel to the uncontrolled use of antibiotics, the emergence of multidrug-resistant
bacteria, like Acinetobacter baumannii, has posed a severe threat. A. baumannii …
bacteria, like Acinetobacter baumannii, has posed a severe threat. A. baumannii …
Identification and construction of a multi-epitopes vaccine design against Klebsiella aerogenes: molecular modeling study
SI Alzarea - Scientific Reports, 2022 - nature.com
A rapid rise in antibiotic resistance by bacterial pathogens is due to these pathogens
adaptation to the changing environmental conditions. Antibiotic resistance infections can be …
adaptation to the changing environmental conditions. Antibiotic resistance infections can be …
Identification of Novel Vaccine Candidates against Multidrug-Resistant Acinetobacter baumannii
DG Moriel, SA Beatson, DJ Wurpel, J Lipman… - PloS one, 2013 - journals.plos.org
Acinetobacter baumannii is an emerging opportunistic bacterium associated with
nosocomial infections in intensive care units. The alarming increase in infections caused by …
nosocomial infections in intensive care units. The alarming increase in infections caused by …
In silico screening of antigenic B-cell derived T-cell epitopes and designing of a multi-epitope peptide vaccine for Acinetobacter nosocomialis
Globally, antibiotic-resistant and tolerated bacterial isolates of Acinetobacter species are
imposing high financial cost on health care systems and as such, molecular targets with …
imposing high financial cost on health care systems and as such, molecular targets with …
Proteomics-based vaccine targets annotation and design of multi-epitope vaccine against antibiotic-resistant Streptococcus gallolyticus
P Chao, X Zhang, L Zhang, A Yang, Y Wang… - Scientific Reports, 2024 - nature.com
Streptococcus gallolyticus is a non-motile, gram-positive bacterium that causes infective
endocarditis. S. gallolyticus has developed resistance to existing antibiotics, and no vaccine …
endocarditis. S. gallolyticus has developed resistance to existing antibiotics, and no vaccine …
Antibiotic Resistance Determinant-Focused Acinetobacter baumannii Vaccine Designed Using Reverse Vaccinology
As one of the most influential and troublesome human pathogens, Acinetobacter baumannii
(A. baumannii) has emerged with many multidrug-resistant strains. After collecting 33 …
(A. baumannii) has emerged with many multidrug-resistant strains. After collecting 33 …
Vaccinomics to design a novel single chimeric subunit vaccine for broad-spectrum immunological applications targeting nosocomial Enterobacteriaceae pathogens
Healthcare associated infections (HAIs) are major cause of elevated mortality, morbidity, and
high healthcare costs. Development of a vaccine targeting these pathogens could benefit in …
high healthcare costs. Development of a vaccine targeting these pathogens could benefit in …
Vaccinomics to Design a Multi-Epitopes Vaccine for Acinetobacter baumannii
Antibiotic resistance (AR) is the result of microbes' natural evolution to withstand the action
of antibiotics used against them. AR is rising to a high level across the globe, and novel …
of antibiotics used against them. AR is rising to a high level across the globe, and novel …
Subtractive proteomics to identify novel drug targets and reverse vaccinology for the development of chimeric vaccine against Acinetobacter baumannii
The emergence of drug-resistant Acinetobacter baumannii is the global health problem
associated with high mortality and morbidity. Therefore it is high time to find a suitable …
associated with high mortality and morbidity. Therefore it is high time to find a suitable …
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