[HTML][HTML] Optimal quantification of contact inhibition in cell populations
Contact inhibition refers to a reduction in the rate of cell migration and/or cell proliferation in
regions of high cell density. Under normal conditions, contact inhibition is associated with …
regions of high cell density. Under normal conditions, contact inhibition is associated with …
Collective and single cell behavior in epithelial contact inhibition
A Puliafito, L Hufnagel, P Neveu… - Proceedings of the …, 2012 - National Acad Sciences
Control of cell proliferation is a fundamental aspect of tissue physiology central to
morphogenesis, wound healing, and cancer. Although many of the molecular genetic factors …
morphogenesis, wound healing, and cancer. Although many of the molecular genetic factors …
Tunable interplay between epidermal growth factor and cell–cell contact governs the spatial dynamics of epithelial growth
Contact-inhibition of proliferation constrains epithelial tissue growth, and the loss of contact-
inhibition is a hallmark of cancer cells. In most physiological scenarios, cell–cell contact …
inhibition is a hallmark of cancer cells. In most physiological scenarios, cell–cell contact …
[HTML][HTML] Stochastic model of contact inhibition and the proliferation of melanoma in situ
MCC Morais, I Stuhl, AU Sabino, WW Lautenschlager… - Scientific reports, 2017 - nature.com
Contact inhibition is a central feature orchestrating cell proliferation in culture experiments;
its loss is associated with malignant transformation and tumorigenesis. We performed a co …
its loss is associated with malignant transformation and tumorigenesis. We performed a co …
Minimal cellular automaton model with heterogeneous cell sizes predicts epithelial colony growth
S Lange, J Schmied, P Willam… - arXiv preprint arXiv …, 2024 - arxiv.org
Regulation of cell proliferation is a crucial aspect of tissue development and homeostasis
and plays a major role in morphogenesis, wound healing, and tumor invasion. A …
and plays a major role in morphogenesis, wound healing, and tumor invasion. A …
A novel method to study contact inhibition of locomotion using micropatterned substrates
E Scarpa, A Roycroft, E Theveneau, E Terriac… - Biology …, 2013 - journals.biologists.com
The concept of contact inhibition of locomotion (CIL) describes the ability of a cell to change
the direction of its movement after contact with another cell. It has been shown to be …
the direction of its movement after contact with another cell. It has been shown to be …
[HTML][HTML] Control of cell colony growth by contact inhibition
Contact inhibition is a cell property that limits the migration and proliferation of cells in
crowded environments. Here we investigate the growth dynamics of a cell colony composed …
crowded environments. Here we investigate the growth dynamics of a cell colony composed …
Contact inhibition (of proliferation) redux
AI McClatchey, AS Yap - Current opinion in cell biology, 2012 - Elsevier
It has long been appreciated that proliferation of many cells is inhibited by density, a
phenomenon that is often attributed to cell–cell contact. The basic properties of this …
phenomenon that is often attributed to cell–cell contact. The basic properties of this …
Nonlinear diffusion and exclusion processes with contact interactions
AE Fernando, KA Landman, MJ Simpson - Physical Review E—Statistical …, 2010 - APS
Exclusion processes on a regular lattice are used to model many biological and physical
systems at a discrete level. The average properties of an exclusion process may be …
systems at a discrete level. The average properties of an exclusion process may be …
[HTML][HTML] Thermodynamic modeling of the statistics of cell spreading on ligand-coated elastic substrates
Biological spread cells exist in a perpetually fluctuating state and therefore cannot be
described in terms of a unique deterministic system. For modeling approaches to provide …
described in terms of a unique deterministic system. For modeling approaches to provide …