[HTML][HTML] A new strategy to fight antimicrobial resistance: the revival of old antibiotics

N Cassir, JM Rolain, P Brouqui - Frontiers in microbiology, 2014 - frontiersin.org
The increasing prevalence of hospital and community-acquired infections caused by
multidrug-resistant (MDR) bacterial pathogens is limiting the options for effective antibiotic …

Multidrug‐resistant bacteria: their mechanism of action and prophylaxis

A Bharadwaj, A Rastogi, S Pandey… - BioMed research …, 2022 - Wiley Online Library
In the present scenario, resistance to antibiotics is one of the crucial issues related to public
health. Earlier, such resistance to antibiotics was limited to nosocomial infections, but it has …

Reviving old antibiotics

U Theuretzbacher, F Van Bambeke… - Journal of …, 2015 - academic.oup.com
In the face of increasing antimicrobial resistance and the paucity of new antimicrobial agents
it has become clear that new antimicrobial strategies are urgently needed. One of these is to …

Future antibiotics scenarios: is the tide starting to turn?

U Theuretzbacher - International journal of antimicrobial agents, 2009 - Elsevier
The fight against multidrug-resistant (MDR) pathogens continues. This article discusses the
gap between the need for new antibiotics and lean research and development (R&D) …

The global need for effective antibiotics: challenges and recent advances

LD Högberg, A Heddini, O Cars - Trends in pharmacological sciences, 2010 - cell.com
The emerging problem of antibiotic resistance is a serious threat to global public health. The
situation is aggravated by a substantial decline in the research and development of …

Pandrug-resistant Gram-negative bacteria: the dawn of the post-antibiotic era?

ME Falagas, IA Bliziotis - International journal of antimicrobial agents, 2007 - Elsevier
The evolving problem of antimicrobial resistance in Pseudomonas aeruginosa,
Acinetobacter baumannii and Klebsiella pneumoniae has led to the emergence of clinical …

Infections by multidrug-resistant Gram-negative Bacteria: What's new in our arsenal and what's in the pipeline?

D Koulenti, A Song, A Ellingboe, MH Abdul-Aziz… - International journal of …, 2019 - Elsevier
The spread of multidrug-resistant bacteria is an ever-growing concern, particularly among
Gram-negative bacteria because of their intrinsic resistance and how quickly they acquire …

A brief history of the antibiotic era: lessons learned and challenges for the future

RI Aminov - Frontiers in microbiology, 2010 - frontiersin.org
This article gives a very brief overview of the antibiotic era, beginning from the discovery of
first antibiotics until the present day situation, which is marred by the emergence of hard-to …

Accelerating resistance, inadequate antibacterial drug pipelines and international responses

U Theuretzbacher - International journal of antimicrobial agents, 2012 - Elsevier
The pandemic of multidrug-resistant (MDR) pathogens and their continuing spread is
beyond dispute. In contrast to the past, today's antibacterial research and development …

Potential of old-generation antibiotics to address current need for new antibiotics

ME Falagas, AP Grammatikos… - Expert review of anti …, 2008 - Taylor & Francis
Despite the constantly increasing need for new antimicrobial agents, antibiotic drug
discovery and development seem to have greatly decelerated in recent years. Presented …