Introduction: There has been a bias in the existing literature on Parkinson's disease (PD)
genetics as most studies involved patients of European ancestry, mostly in Europe and …

Abstract Background Genetic heterogeneity in Parkinson's disease (PD) has been
unambiguously reported across different populations. Assuming a higher genetic load, we …

Parkinson'disease (PD) is a common neurodegenerative disease with the pathological
hallmark of α-synuclein aggregation within dopaminergic neurons. The etiology of PD …

Parkinson's disease (PD) is a global health challenge, yet historically studies of PD have
taken place predominantly in European populations. Recent genetics research conducted in …

This study aimed to determine the mutational spectrum of familial Parkinson's disease and
sporadic early-onset Parkinson's disease (sEOPD) in a mainland Chinese population and …

Human genetics research lacks diversity; over 80% of genome-wide association studies
(GWAS) have been conducted on individuals of European ancestry. In addition to limiting …

So far, over 20 causative genes of monogenic Parkinson's disease (PD) have been
identified. Some causative genes of non-parkinsonian entities may also manifest with …

Over the last decades, genetics has been the engine that has pushed us along on our
voyage to understand the etiology of Parkinson's disease (PD). Although a large number of …

Objective To examine the genetic variability of Estonian Parkinson's disease (PD) patients
using an ongoing epidemiological study in combination with a genetic analysis. Methods …

To date, a large spectrum of genetic variants has been related to familial and sporadic
Parkinson's disease (PD) in diverse populations worldwide. However, very little is known …