The widely-expressed molecule CD38 is a single-stranded type II transmembrane
glycoprotein that is mainly involved in regulating the differentiation and activation state of the …

The CD38 molecule was one of the first markers to be identified on human lymphocytes [1–
3]. As CD38 was brightly expressed on dividing cells including haematopoietic cells …

The analysis of CD38 expression on lymphocytes has become an important tool for
monitoring patients during HIV-1 infection and has recently been proposed for use in the …

ABSTRACT CD38 displays lateral association with the HIV‐1 receptor CD4. This association
is potentiated by the HIV‐1 envelope glycoprotein gp120. The aim of this work was to …

Despite abundant evidence associating CD38 overexpression and CD4 T cell depletion in
HIV infection, no causal relation has been investigated. To address this issue, a series of …

As in other viral infections, human immunodeficiency virus type 1 (HIV-1) induces an
immune response, which translates into an increased lymphoid activation, despite CD4+ T …

CD38 is a progression marker in HIV‐1 infection, it displays lateral association with CD4,
and down‐modulates gp120/CD4 binding. The aim of this study was to elucidate the …

The expression of CD38 on CD8+ T-lymphocyte is a significant predictive value in disease
progression of HIV infected individuals and in monitoring a response to therapy. CD38 …

CD38 is a multifunctional receptor and enzyme present on the surface of B lymphocytes,
which can induce B lymphocytes proliferation and apoptosis by crosslinking related …

CD38 is a multifunctional protein widely expressed in cells from the immune system and as
a soluble form in biological fluids. CD38 expression is up-regulated by an array of …