Annexin 1 has been shown to participate through its unique N-terminal domain in the
recruitment and activation of leukocytes at sites of inflammation. Peptides derived from this …

Specific binding sites for the anti‐inflammatory protein annexin I have been detected on the
surface of human monocytes and polymorphonuclear leukocytes (PMN). These binding sites …

A hallmark of inflammation is the mobilization of blood-borne leukocytes across
microvessels to kill and remove the invading pathogen. For its damaging potential, leukocyte …

Recombinant human annexin I and a monoclonal antibody specific for this protein (mAb 1B)
were used to investigate surface binding of this member of the annexin family of proteins to …

Annexins are soluble proteins capable of binding to phospholipid membranes in a calcium-
dependent manner. Annexin 3, a 33 kDa protein mainly expressed in neutrophils …

Annexin I, a member of the calcium-and phospholipid-binding annexin superfamily of
proteins, is largely present in human neutrophils. To determine its exact intracellular …

Annexin 1 is an anti-inflammatory protein that plays a key role in innate immunity by
modulating the activation of several types of cells, including neutrophils. Here we have …

When cells undergo apoptosis, or programmed cell death, they expose phosphatidylserine
(PS) on their surface. Macrophages that efficiently phagocytose apoptotic cells also express …

Annexin III, a putative inositol (1, 2)-phosphohydrolase, was co-crystallized with inositol 2-
phosphate, the inhibitor of the reaction, and its structure was solved to 1.95 Å resolution. No …

A truncated form of annexin I, formed during Ca2+-induced translocation to neutrophil
specific granules and secretory vesicles/plasma membranes, is generated through the …