Of the many slow-acting neurotransmitters utilized by concentration (50 μM) in virtually all
medium spiny the mammalian central nervous system, dopamine has neurons (Ouimet et …

The dopamine-and cAMP-regulated phosphoprotein, Mr 32 kDa (DARPP-32), plays a key
role in dopaminoceptive neurons in the neostriatum (and likely in other brain regions) in …

DARPP-32 is a neuronal phosphoprotein that is specifically enriched in neurons possessing
D1 dopamine receptors, including the medium-sized spiny neurons of the striatum. DARPP …

Immunocytochemical studies have been carried out to determine the regional and cellular
distribution of DARPP-32, a protein the phosphorylation of which can be regulated by …

Immunohistochemical double-label techniques were used to study the localization of
DARPP-32, a phosphoprotein that is enriched in neurons possessing members of the D 1 …

DARPP-32, a dopamine and cAMP-regulated phosphoprotein with an apparent molecular
weight of 32 kD, is enriched in dopaminoceptive brain regions. Chief among these regions is …

Dopamine and cAMP-regulated phosphoprotein of M r 32,000 (DARPP-32) plays an
obligatory role in most of the actions of dopamine. In resting neostriatal slices, cyclin …

Dopaminergic neurons exert a major modulatory effect on the forebrain. Dopamine and
adenosine 3′, 5′-monophosphate–regulated phosphoprotein (32 kilodaltons)(DARPP …

Mice lacking DARPP-32, a striatal-enriched phosphoprotein, show abnormal behavioral and
biochemical responses to cocaine, but the role of individual phosphorylation sites in DARPP …

Drugs of abuse share the ability to enhance dopaminergic neurotransmission in the dorsal
and ventral striatum. The action of dopamine is modulated by additional neurotransmitters …