The role of anti-inflammatory drugs in colorectal cancer

D Wang, RN DuBois - Annual review of medicine, 2013 - annualreviews.org
A large body of evidence indicates that genetic mutations, epigenetic changes, chronic
inflammation, diet, and lifestyle are key risk factors for colorectal cancer (CRC). Prevention of …

Clinically relevant anti-inflammatory agents for chemoprevention of colorectal cancer: new perspectives

A Mohammed, NS Yarla, V Madka, CV Rao - International journal of …, 2018 - mdpi.com
Substantial efforts are underway for prevention of early stages or recurrence of colorectal
cancers (CRC) or new polyp formation by chemoprevention strategies. Several …

New strategies for colorectal cancer prevention and treatment

D Saha, C Roman, RD Beauchamp - World journal of surgery, 2002 - search.proquest.com
Colorectal cancer (CRC) is the second most common fatal malignancy in the Western world,
with more than 150,000 new cases accounting for 55,000 deaths in the United States every …

Chemoprevention in gastrointestinal physiology and disease. Anti-inflammatory approaches for colorectal cancer chemoprevention

AM Fajardo, GA Piazza - American Journal of Physiology …, 2015 - journals.physiology.org
Colorectal cancer (CRC) is one of the most common human malignancies and a leading
cause of cancer-related deaths in developed countries. Identifying effective preventive …

The evolving role of nonsteroidal anti-inflammatory drugs in colon cancer prevention: a cause for optimism

B Rigas, GJ Tsioulias - Journal of Pharmacology and Experimental …, 2015 - ASPET
Colorectal cancer (CRC) is a serious yet preventable disease. The low acceptance and cost
of colonoscopy as a screening method for CRC make chemoprevention an important option …

Potential role of non-steroidal anti-inflammatory drugs in colorectal cancer chemoprevention for inflammatory bowel disease: An umbrella review

P Newman, J Muscat - Cancers, 2023 - mdpi.com
Simple Summary Non-steroidal anti-inflammatory drugs prevent the recurrence of
adenomatous polyps and colon cancer. At low doses, with presumed low gastrotoxicity …

Chemoprevention of colorectal cancer

K Gwyn, FA Sinicrope - Official journal of the American College of …, 2002 - journals.lww.com
Colorectal cancer is the third most incident cancer in the United States and is second only to
lung cancer as a cause of cancer-related mortality. Colorectal cancer develops through a …

Anti-inflammatory phytochemicals for chemoprevention of colon cancer

V Madka, CV Rao - Current cancer drug targets, 2013 - ingentaconnect.com
Every year more than a million new cancer cases and 600,000 deaths are reported world-
wide. Colorectal cancer is the fourth most commonly occurring and second leading cause of …

the potential of combinational regimen with non‐steroidal anti‐inflammatory drugs in the chemoprevention of colorectal cancer

M Jalving, JJ Koornstra, S De Jong… - Alimentary …, 2005 - Wiley Online Library
Non‐steroidal anti‐inflammatory drugs are chemopreventive agents in colorectal cancer.
Non‐steroidal anti‐inflammatory drugs do not, however, offer complete protection against …

Inflammatory markers are associated with risk of colorectal cancer and chemopreventive response to anti-inflammatory drugs

AT Chan, S Ogino, EL Giovannucci, CS Fuchs - Gastroenterology, 2011 - Elsevier
BACKGROUND & AIMS: Aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs) lower
the risk of colorectal cancer (CRC). We investigated whether plasma inflammatory markers …