[HTML][HTML] Detecting laryngopharyngeal reflux in patients with upper airways symptoms: symptoms, signs or salivary pepsin?

A Spyridoulias, S Lillie, A Vyas, SJ Fowler - Respiratory medicine, 2015 - Elsevier
Background Laryngopharyngeal reflux (LPR) can induce laryngeal hyper-responsiveness, a
unifying feature underlying chronic cough and vocal cord dysfunction. The diagnosis of LPR …

Laryngopharyngeal reflux: symptoms, signs, and presence of pepsin in saliva-a reliable diagnostic triad

S Divakaran, S Rajendran, RM Thomas… - International …, 2021 - thieme-connect.com
Introduction Twenty-four-hour multichannel intraluminal impedance with double probe pH
monitoring (MII-pH), though considered the most sensitive tool for the diagnosis of …

The diagnostic usefullness of the salivary pepsin test in symptomatic laryngopharyngeal reflux

L Barona-Lleo, R Barona-De Guzman, C Krstulovic - Journal of Voice, 2019 - Elsevier
Summary Objective Laryngopharyngeal Reflux (LPR) is a disease characterized by the
presence of symptoms, signs and tissue alterations in the aero-digestive upper tract as a …

Pepsin and oropharyngeal pH monitoring to diagnose patients with laryngopharyngeal reflux

M Weitzendorfer, SA Antoniou, P Schredl… - The …, 2020 - Wiley Online Library
Objectives The aim of this study was to compare the diagnostic accuracy of salivary pepsin
with oropharyngeal pH monitoring using the Restech measurement system (Dx‐pH) for the …

Abilities of oropharyngeal pH tests and salivary pepsin analysis to discriminate between asymptomatic volunteers and subjects with symptoms of laryngeal irritation

R Yadlapati, C Adkins, DM Jaiyeola, AK Lidder… - Clinical …, 2016 - Elsevier
Background & Aims It has been a challenge to confirm the association between laryngeal
symptoms and physiological reflux disease. We examined the ability of oropharyngeal pH …

Salivary Pepsin Test: Useful and simple tool for the laryngopharyngeal reflux diagnosis

L Barona-Lleó, C Duval… - Acta Otorrinolaringologica …, 2018 - Elsevier
Introduction and objectives Laryngopharyngeal reflux (LPR) is a disease characterized by
the presence of symptoms, signs and tissue damage caused by retrograde flow of gastric …

Symptoms classically attributed to laryngopharyngeal reflux correlate poorly with pharyngeal reflux events on multichannel intraluminal impedance testing

S Salgado, LF Borges, JX Cai, WK Lo… - Diseases of the …, 2023 - academic.oup.com
Laryngopharyngeal reflux (LPR) is thought to be a common etiology of throat and airway
symptoms. Diagnosis of LPR is challenging, given the variable symptomatology and …

Mucosal changes in laryngopharyngeal reflux—prevalence, sensitivity, specificity and assessment

J Powell, HC Cocks - The Laryngoscope, 2013 - Wiley Online Library
Objectives/Hypothesis: A literature review regarding the use of laryngopharyngeal mucosal
signs in diagnosing laryngopharyngeal reflux (LPR). Study Design: Literature review …

[PDF][PDF] The role of pepsin in the laryngopharyngeal reflux

K Kowalik, A Krzeski - Polish Journal of Otolaryngology, 2017 - bibliotekanauki.pl
Laryngopharyngeal reflux (LPR) is a common defect among laryngological and phoniatric
patients. Although LPR is categorized as a superficial gastroesophageal reflux disease …

Saliva pepsin detection and proton pump inhibitor response in suspected laryngopharyngeal reflux

CP Wang, CC Wang, HC Lien, WJ Lin… - The …, 2019 - Wiley Online Library
Objectives/Hypothesis To evaluate the prediction value of saliva pepsin detection for an 8‐
week proton pump inhibitor (PPI) response in patients with a Reflux Symptoms Index (RSI) …