Importance Observational studies have reported that statin use may be associated with
improved outcomes of various infections. Ventilator-associated pneumonia (VAP) is the most …

ABSTRACT BACKGROUND Statins are prescribed to lower cholesterol, but also have anti-
inflammatory properties. Some observational studies suggest that statins may reduce …

Objective: To investigate whether the use of pravastatin reduces the frequency of ventilator-
associated pneumonia and whether it is related to favorable outcomes in critical care …

Objective: To examine the association of statin use with clinical outcomes and circulating
biomarkers in community-acquired pneumonia and sepsis. Design: Multicenter inception …

BACKGROUND: Statins have potent anti-inflammatory effects in laboratory studies of
pulmonary inflammation. We investigated whether statin users had improved outcome when …

Objectives To determine whether statins reduce mortality or need for admission to intensive
care in patients admitted to hospital with community acquired pneumonia; and to assess …

Background While some experimental and clinical research suggests that statins improve
outcomes after severe infections, the evidence for pneumonia is conflicting. We examined …

Objective Examine the impact of previous statin therapy on hospital mortality and whether it
is due to a protective effect against ICU-acquired infections. Design and setting Cohort …

Background Recent studies suggest that HMG-CoA reductase inhibitors (" statins") may
have beneficial effects for patients at risk for some types of infections. We examined the …

OBJECTIVE: The objective of this study was to perform a systematic review and meta-
analysis of the effects of statins on mortality following pneumonia. METHODS: We searched …