Mitochondria are essential organelles that execute and coordinate various metabolic
processes in the cell. Mitochondrial dysfunction severely affects cell fitness and contributes …

The maintenance of a healthy and functional mitochondrial network is critical during
development as well as throughout life in the response to physiological adaptations and …

Mitochondrial dysfunction has long been associated with the aging process and the onset of
numerous diseases. Regulation of the complex protein-folding environment within the …

As a central hub of cellular metabolism and signaling, the mitochondrion is a crucial
organelle whose dysfunction can cause disease and whose activity is intimately connected …

Mitochondria serve as a hub for many cellular processes, including bioenergetics,
metabolism, cellular signaling, redox balance, calcium homeostasis, and cell death. The …

Abstract Mitochondria contain about 1,000–1,500 proteins that fulfil multiple functions.
Mitochondrial proteins originate from two genomes: mitochondrial and nuclear. Hence …

Mitochondrial function is key for maintaining cellular health, while mitochondrial failure is
associated with various pathologies, including inherited metabolic disorders and age …

Mitochondria are essential organelles important for energy production, proliferation, and cell
death. Biogenesis, homeostasis, and degradation of this organelle are tightly controlled to …

Mitochondria are essential constituents of a eukaryotic cell by supplying ATP and
contributing to many mayor metabolic processes. As endosymbiotic organelles, they …

Mitochondria are organelles central to myriad cellular processes. To maintain mitochondrial
health, various processes co-operate at both the molecular and organelle level. At the …