Using experimental data and information criteria to guide model selection for reaction–diffusion problems in mathematical biology

DJ Warne, RE Baker, MJ Simpson - Bulletin of Mathematical Biology, 2019 - Springer
Reaction–diffusion models describing the movement, reproduction and death of individuals
within a population are key mathematical modelling tools with widespread applications in …

Parameter identifiability and model selection for partial differential equation models of cell invasion

Y Liu, K Suh, PK Maini, DJ Cohen… - Journal of the Royal …, 2024 - royalsocietypublishing.org
When employing mechanistic models to study biological phenomena, practical parameter
identifiability is important for making accurate predictions across wide ranges of unseen …

Learning equations from biological data with limited time samples

JT Nardini, JH Lagergren, A Hawkins-Daarud… - Bulletin of mathematical …, 2020 - Springer
Equation learning methods present a promising tool to aid scientists in the modeling process
for biological data. Previous equation learning studies have demonstrated that these …

Conflicting biomedical assumptions for mathematical modeling: the case of cancer metastasis

A Divoli, EA Mendonça, JA Evans… - PLoS computational …, 2011 - journals.plos.org
Computational models in biomedicine rely on biological and clinical assumptions. The
selection of these assumptions contributes substantially to modeling success or failure …

[HTML][HTML] Modelling count data with partial differential equation models in biology

MJ Simpson, RJ Murphy, OJ Maclaren - Journal of Theoretical Biology, 2024 - Elsevier
Partial differential equation (PDE) models are often used to study biological phenomena
involving movement-birth–death processes, including ecological population dynamics and …

Methods of model reduction for large-scale biological systems: a survey of current methods and trends

TJ Snowden, PH van der Graaf, MJ Tindall - Bulletin of mathematical …, 2017 - Springer
Complex models of biochemical reaction systems have become increasingly common in the
systems biology literature. The complexity of such models can present a number of …

Bayesian parameter identification for turing systems on stationary and evolving domains

E Campillo-Funollet, C Venkataraman… - Bulletin of mathematical …, 2019 - Springer
In this study, we apply the Bayesian paradigm for parameter identification to a well-studied
semi-linear reaction–diffusion system with activator-depleted reaction kinetics, posed on …

Bayesian calibration, validation, and uncertainty quantification of diffuse interface models of tumor growth

A Hawkins-Daarud, S Prudhomme… - Journal of mathematical …, 2013 - Springer
The idea that one can possibly develop computational models that predict the emergence,
growth, or decline of tumors in living tissue is enormously intriguing as such predictions …

Practical parameter identifiability for spatio-temporal models of cell invasion

MJ Simpson, RE Baker… - Journal of the …, 2020 - royalsocietypublishing.org
We examine the practical identifiability of parameters in a spatio-temporal reaction–diffusion
model of a scratch assay. Experimental data involve fluorescent cell cycle labels, providing …

[HTML][HTML] Generative models of morphogenesis in developmental biology

NR Stillman, R Mayor - Seminars in Cell & Developmental Biology, 2023 - Elsevier
Understanding the mechanism by which cells coordinate their differentiation and migration
is critical to our understanding of many fundamental processes such as wound healing …