Avian coccidiosis brings tremendous economic loss to the poultry industry worldwide. The
third generation vaccine, including subunit and DNA vaccines, exhibited promising …

Introduction Avian coccidiosis, caused by apicomplexan protozoa belonging to the Eimeria
genus, is considered one of the most important diseases in the intensive poultry industry …

Rhomboid-like proteases (ROMs) are considered as new candidate antigens for developing
new-generation vaccines due to their important role involved in the invasion of …

Eimeria maxima (E. maxima) is one of the most prevalent species that causes chicken
coccidiosis on chicken farms. During apicomplexan protozoa invasion, rhomboid-like …

A consensus is that the Th1 immune response plays a predominant role against avian
coccidiosis. Therefore, an antigen with the ability to induce Th1 cytokine responses is an …

E. mitis is ubiquitous in clinical coccidiosis caused by mixed infection of Eimeria species and
the infection by E. mitis usually significantly impairs productivity of the infected chickens. To …

Avian coccidiosis arises from co-infection involving multiple Eimeria species, which could
give rise to substantial economic losses in the global poultry industry. As a result, multivalent …

Avian coccidiosis caused by Eimeria is a serious parasitic disease that poses a threat to the
poultry industry. Currently, prevention and treatment mainly rely on the administration of …

Background Rhoptry organelle proteins (ROPs) secreted by apicomplexan parasites play
important roles during parasites invasion and survival in host cells, and are potential vaccine …

Chicken coccidiosis caused by Eimeria species leads to tremendous economic losses to the
avian industry worldwide. Identification of parasite life cycle specific antigens is a critical step …