Using the collaborative cross to identify the role of host genetics in defining the murine gut microbiome
A Nagarajan, K Scoggin, J Gupta, DW Threadgill… - Microbiome, 2023 - Springer
Background The human gut microbiota is a complex community comprised of trillions of
bacteria and is critical for the digestion and absorption of nutrients. Bacterial communities of …
bacteria and is critical for the digestion and absorption of nutrients. Bacterial communities of …
Host genetic and environmental effects on mouse intestinal microbiota
JH Campbell, CM Foster, T Vishnivetskaya… - The ISME …, 2012 - academic.oup.com
The mammalian gut harbors complex and variable microbial communities, across both host
phylogenetic space and conspecific individuals. A synergy of host genetic and …
phylogenetic space and conspecific individuals. A synergy of host genetic and …
Murine genetic background has a stronger impact on the composition of the gut microbiota than maternal inoculation or exposure to unlike exogenous microbiota
H Korach-Rechtman, S Freilich… - Applied and …, 2019 - Am Soc Microbiol
The gut microbiota is a complex ecosystem, affected by both environmental factors and host
genetics. Here, we aim at uncovering the bacterial taxa whose gut persistence is controlled …
genetics. Here, we aim at uncovering the bacterial taxa whose gut persistence is controlled …
Taxonomic composition and variation in the gut microbiota of laboratory mice
J Yang, J Chun - Mammalian Genome, 2021 - Springer
The gut microbiota can affect host health, including humans. Mouse models have been used
extensively to study the relationships between the host and the gut microbiota. With the …
extensively to study the relationships between the host and the gut microbiota. With the …
Inflammation-associated enterotypes, host genotype, cage and inter-individual effects drive gut microbiota variation in common laboratory mice
F Hildebrand, TLA Nguyen, B Brinkman, RG Yunta… - Genome biology, 2013 - Springer
Background Murine models are a crucial component of gut microbiome research.
Unfortunately, a multitude of genetic backgrounds and experimental setups, together with …
Unfortunately, a multitude of genetic backgrounds and experimental setups, together with …
Individuality in gut microbiota composition is a complex polygenic trait shaped by multiple environmental and host genetic factors
AK Benson, SA Kelly, R Legge, F Ma… - Proceedings of the …, 2010 - National Acad Sciences
In vertebrates, including humans, individuals harbor gut microbial communities whose
species composition and relative proportions of dominant microbial groups are …
species composition and relative proportions of dominant microbial groups are …
Impact of host genetics on gut microbiome: Take‐home lessons from human and mouse studies
I Cahana, FA Iraqi - Animal models and experimental medicine, 2020 - Wiley Online Library
The intestinal microbiome has emerged as an important component involved in various
diseases. Therefore, the interest in understanding the factors shaping its composition is …
diseases. Therefore, the interest in understanding the factors shaping its composition is …
Identifying gut microbe–host phenotype relationships using combinatorial communities in gnotobiotic mice
Identifying a scalable, unbiased method for discovering which members of the human gut
microbiota influence specific physiologic, metabolic, and immunologic phenotypes remains …
microbiota influence specific physiologic, metabolic, and immunologic phenotypes remains …
Murine gut microbiota is defined by host genetics and modulates variation of metabolic traits
The gastrointestinal tract harbors a complex and diverse microbiota that has an important
role in host metabolism. Microbial diversity is influenced by a combination of environmental …
role in host metabolism. Microbial diversity is influenced by a combination of environmental …
The Mouse Gastrointestinal Bacteria Catalogue enables translation between the mouse and human gut microbiotas via functional mapping
BS Beresford-Jones, SC Forster, MD Stares, G Notley… - Cell host & …, 2022 - cell.com
Human health and disease have increasingly been shown to be impacted by the gut
microbiota, and mouse models are essential for investigating these effects. However, the …
microbiota, and mouse models are essential for investigating these effects. However, the …