MEG3: an oncogenic long non-coding RNA in different cancers

A Al-Rugeebah, M Alanazi, NR Parine - Pathology & Oncology Research, 2019 - Springer
Long noncoding RNAs (lncRNAs) have recently considered as central regulators in diverse
biological processes and emerged as vital players controlling tumorigenesis. Several …

[HTML][HTML] Potential applications of MEG3 in cancer diagnosis and prognosis

Y He, Y Luo, B Liang, L Ye, G Lu, W He - Oncotarget, 2017 - ncbi.nlm.nih.gov
LncRNAs are emerging as integral functional and regulatory components of normal
biological activities and are now considered as critically involved in the development of …

[HTML][HTML] A review of current evidence about lncRNA MEG3: A tumor suppressor in multiple cancers

J Xu, X Wang, C Zhu, K Wang - Frontiers in cell and developmental …, 2022 - frontiersin.org
Long non-coding RNA (lncRNA) maternally expressed gene 3 (MEG3) is a lncRNA located
at the DLK1-MEG3 site of human chromosome 14q32. 3. The expression of MEG3 in various …

[HTML][HTML] Long non-coding RNA MEG3 functions as a competing endogenous RNA to regulate gastric cancer progression

W Peng, S Si, Q Zhang, C Li, F Zhao, F Wang… - Journal of experimental …, 2015 - Springer
Abstract Background Long noncoding RNAs (lncRNAs) have recently emerged as important
regulators in governing fundamental biological processes, and many of which are likely to …

Long noncoding RNA MEG3 inhibits breast cancer growth via upregulating endoplasmic reticulum stress and activating NF‐κB and p53

Y Zhang, J Wu, H Jing, G Huang… - Journal of cellular …, 2019 - Wiley Online Library
Long noncoding RNA (lncRNA) maternally expressed 3 (MEG3) has been implicated as a
tumor suppressor gene in several human cancer types. However, little is known regarding its …

[HTML][HTML] Maternally expressed gene 3 (MEG3): A tumor suppressor long non coding RNA

S Ghafouri-Fard, M Taheri - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Abstract Maternally expressed gene 3 (MEG3) is a long non-coding RNA (lncRNA) located
on chromosome 14q32. 3. Direct sequencing experiments have shown monoallelic …

Overexpression of long non-coding RNA MEG3 suppresses breast cancer cell proliferation, invasion, and angiogenesis through AKT pathway

C Zhang, M Yu, X Li, Z Zhang, C Han… - Tumor Biology, 2017 - journals.sagepub.com
Long non-coding RNA MEG3 has been identified as a tumor suppressor which plays
important roles in tumorigenesis; however, its potential role in breast cancer has not been …

Downregulated long noncoding RNA MEG3 is associated with poor prognosis and promotes cell proliferation in gastric cancer

M Sun, R Xia, F Jin, T Xu, Z Liu, W De, X Liu - Tumor Biology, 2014 - Springer
Long noncoding RNAs (lncRNAs) have emerged recently as major players in governing
fundamental biological processes, and many of which are altered in expression and likely to …

[HTML][HTML] Long non-coding RNA MEG3 functions as a tumour suppressor and has prognostic predictive value in human pancreatic cancer

L Ma, F Wang, C Du, Z Zhang, H Guo… - Oncology …, 2018 - spandidos-publications.com
Long non-coding RNA (lncRNA) MEG3 has been demonstrated to be a tumour suppressor
in many malignancies. However, the functional role of MEG3 in pancreatic cancer (PC) is …

Decreased expression of long noncoding RNA MEG3 affects cell proliferation and predicts a poor prognosis in patients with colorectal cancer

D Yin, Z Liu, E Zhang, R Kong, Z Zhang, R Guo - Tumor Biology, 2015 - Springer
Colorectal cancer (CRC) remains an important public health problem in the world. Long
noncoding RNA (lncRNA) is an RNA molecular that is longer than 200 nucleotides and …