Here, we investigated the possible anti-cancer properties of bromelain in Kras mutant
human colorectal carcinoma cell lines and a mouse model harboring a Kras mutation. Cell …

Cetuximab is approved for the treatment of metastatic colorectal cancer (mCRC) with RAS
wild-type. Nevertheless, the prognosis remains poor and the effectiveness of cetuximab is …

Simple Summary Sodium butyrate (NaB) is a short-chain fatty acid produced by intestinal
microbial fermentation of dietary fiber. It has been shown to be effective in inhibiting …

Ferroptosis is an iron-dependent, oxidative cell death, and is characterized by iron-
dependent accumulation of reactive oxygen species (ROS) within the cell. It has been …

Extensive use of substances derived from natural sources has been documented in the
treatment of colorectal cancer (CRC). Lysionotin (Lys) is a flavonoid present in the flowers …

Colon cancer continues to be a prevalent gastrointestinal malignancy with a bleak
prognosis. The induction of ferroptosis, a new form of regulated cell death, has emerged as …

Ferroptosis, a new form of regulated cell death triggered by the iron-dependent peroxidation
of phospholipids, is associated with cellular metabolism, redox homeostasis, and various …

Ferroptosis, a type of cell death triggered by excessive accumulation of iron-dependent lipid
peroxidation, possesses an excellent potential in cancer treatment. However, many …

Background and Purpose: RAS mutations limit the effectiveness of anti-epidermal growth
factor receptor (EGFR) monoclonal antibodies in combination with chemotherapy for …

Primary liver cancer is the third leading cause of cancer death in the world, and the lack of
effective treatments is the main reason for the high mortality. Corosolic acid (CA) has been …