Osteoarthritis (OA) is one of the most common diseases leading to physical disability, with
age being the main risk factor, and degeneration of articular cartilage is the main focus for …

Chondrocytes are the only cell type in normal cartilage. The pathological changes of
osteoarthritis (OA) mostly revolve around the apoptosis and dysfunction of chondrocytes …

Autophagy is an intracellular degradation system that maintains the stable state of cell
energy metabolism. Some recent findings have indicated that autophagy dysfunction is an …

Chondrocytes are the sole cellular constituents of normal cartilage. The degeneration and
apoptosis of these cells are considered the main cause of osteoarthritis (OA). Previous …

Osteoarthritis is characterized by continuous degeneration of articular cartilage resulting in
disability. The death of chondrocytes and the loss of the extracellular matrix are the central …

The present study aimed to analyze the responses to autophagy in osteoarthritis (OA) and
aging chondrocytes in order to elucidate the role of autophagy in the pathogenesis of OA …

Autophagy, as a fundamental mechanism for cellular homeostasis, is generally involved in
the occurrence and progression of various diseases. Osteoarthritis (OA) is the most common …

Degradation of the articular cartilage is at the centre of the pathogenesis of osteoarthritis
(OA), for which age is the major risk factor. Maintaining the chondrocytes in a healthy …

Osteoarthritis (OA) is a degenerative disease that leads to joint pain and stiffness and is one
of the leading causes of disability and pain worldwide. Autophagy is a highly conserved self …

Osteoarthritis (OA) is an age-related degenerative disease characterized by cartilage
degeneration and abnormal bone remodeling in the subchondral bone. Autophagy …